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Gene Expression Data
Assay Details
Assay
Reference: J:79481 Yu J, et al., Sonic hedgehog regulates proliferation and differentiation of mesenchymal cells in the mouse metanephric kidney. Development. 2002 Nov;129(22):5301-12
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7414055
Gene symbol: Acta2
Gene name: actin alpha 2, smooth muscle, aorta
Antibody: anti-smooth muscle alpha-actin
Detection system: Alexa Fluor 568
Results
Specimen 8A: postnatal newborn (more )
Note: Double labeled: red - Acta2; green - DBA (lectin).
Structure Level Pattern Image Note
TS27: ureteral smooth muscle layer smooth muscle component Present 8A Expression in ureter smooth muscle.
TS27: ureter Present Regionally restricted 8A No expression in 1-2 layers of ureteral mesenchymal cells between smooth muscla and ureteral epithelium.

Specimen 8B: postnatal newborn; Shhtm1Amc/Shhtm2Amc, Tg(Hoxb7-cre)13Amc/0 (more )
Note: Conditional mutant. Double labeled: red - Acta2; green - DBA (lectin).
Structure Level Pattern Image Note
TS27: ureteral smooth muscle layer smooth muscle component Present 8B Expression in ureter smooth muscle.

Specimen 8D: postnatal newborn; Ptch1tm1Mps/Ptch1+ (more )
Note: Triple labeled: red - Acta2; green - DBA (lectin); black - Ptch1 reporter (assay MGI:7414056).
Structure Level Pattern Image Note
TS27: ureter Present Regionally restricted 8D No expression in Ptch-expressing cells directly adjacent to epithelium.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory