Del(15Rr334-Cyrib)14Fsp
Transposon induced Allele Detail
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| Symbol: |
Del(15Rr334-Cyrib)14Fsp |
| Name: |
deletion, Chr 15, Francois Spitz 14 |
| MGI ID: |
MGI:7411367 |
| Synonyms: |
del(13-20) |
| Gene: |
Del(15Rr334-Cyrib)14Fsp Location: unknown Genetic Position: Chr15, Syntenic
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| Strain of Origin: |
Not Applicable
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| Allele Type: |
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Transposon induced (Conditional ready, Modified regulatory region, Null/knockout, Reporter) |
| Mutations: |
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Intergenic deletion, Intragenic deletion
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Del(15Rr334-Cyrib)14Fsp involves 28 genes/genome features (Gm49019, Rr334, Gm41335 ...)
View all
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Mutation details: Cre-mediated inter-chromosomal recombination between Tn(sb-SBlac)15.194575Fsp at chr15:63175856-63175857 (GRCm39) and Tn(sb-SBlac)15.192331Fsp at chr15:63871640-63871641 deleted approximately 696 kb and leaves one intact copy of the transposon cassette (in reverse orientation) at the deletion junction. The transposon consists of a Sleeping Beauty transposon inverted repeat, loxP site, human beta-globin HBB minimal promoter, the lacZ beta-galactosidase reporter gene, SV40 poly(A) signal sequence, and a Sleeping Beauty transposon direct repeat. This deletion is the complement of duplication Dp(15Rr334-Cyrib)1Fsp. The centromeric part of the deleted sequence is part of the Myc topologically associating domain (TAD) and the deletion deletes Myc enhancers Rr334, Rr316124, Rr313933, Rr331, Rr307328, Rr332, Rr307330, Rr333, Rr313939 and Rr313944, the Gsdmc gene cluster, and the 3' end of Cyrib.
(J:212391)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Del(15Rr334-Cyrib)14Fsp Mutation: |
0 strains or lines available
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| Original: |
J:212391 Uslu VV, et al., Long-range enhancers regulating Myc expression are required for normal facial morphogenesis. Nat Genet. 2014 Jul;46(7):753-8 |
| All: |
1 reference(s) |
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