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Gene Expression Data
Assay Details
Assay
Reference: J:324175 Su YC, et al., YAP maintains the production of intermediate progenitor cells and upper-layer projection neurons in the mouse cerebral cortex. Dev Dyn. 2022 May;251(5):846-863
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7378744
Gene symbol: Mki67
Gene name: antigen identified by monoclonal antibody Ki 67
Antibody: anti-Ki67
Detection system: Secondary antibody coupled to DyLight 549
Results
Specimen 8A: embryonic day 16.5; Yap1tm1.1Dupa/Yap1tm1.1Dupa (more )
Note: Double labeled: green - Mki67; red - EdU.
Structure Level Pattern Image Note
TS24: cerebral cortex ventricular layer Present 8A , 8A'
TS24: cerebral cortex subventricular zone Present 8A' , 8A
TS24: cerebral cortex intermediate zone Present 8A' , 8A

Specimen 8B: embryonic day 16.5; Tg(Nes-cre)1Kln/0, Yap1tm1.1Dupa/Yap1tm1.1Dupa (more )
Note: Conditional mutant. Double labeled: green - Mki67; red - EdU.
Structure Level Pattern Image Note
TS24: cerebral cortex ventricular layer Present 8B , 8B' Percentage of double-expressing cells similar to that of control.
TS24: cerebral cortex subventricular zone Weak 8B' , 8B Percentage of double-expressing cells decreased compared to that of control
TS24: cerebral cortex intermediate zone Present 8B , 8B' Percentage of double-expressing cells similar to that of control.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory