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Gene Expression Data
Assay Details
Assay
Reference: J:324175 Su YC, et al., YAP maintains the production of intermediate progenitor cells and upper-layer projection neurons in the mouse cerebral cortex. Dev Dyn. 2022 May;251(5):846-863
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7378743
Gene symbol: Eomes
Gene name: eomesodermin
Antibody: anti-TBR2
Detection system: Secondary antibody coupled to DyLight 549
Results
Specimen 7A: embryonic day 15.5; Yap1tm1.1Dupa/Yap1tm1.1Dupa (more )
Structure Level Pattern Image Note
TS23: cerebral cortex ventricular layer Weak 7A
TS23: cerebral cortex subventricular zone Present 7A Most expressing cell located in subventricular zone.
TS23: cerebral cortex intermediate zone Weak 7A

Specimen 7B: embryonic day 15.5; Tg(Nes-cre)1Kln/0, Yap1tm1.1Dupa/Yap1tm1.1Dupa (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: cerebral cortex ventricular layer Weak 7B Density of expressing cells similar to that of controls.
TS23: cerebral cortex subventricular zone Present 7B Density of expressing cells similar to that of controls.
TS23: cerebral cortex intermediate zone Present 7B Density of expressing cells increased compared to controls.

Specimen 7G,G': embryonic day 18.5; Yap1tm1.1Dupa/Yap1tm1.1Dupa (more )
Structure Level Pattern Image Note
TS26: cerebral cortex ventricular layer Weak 7G' , 7G
TS26: cerebral cortex subventricular zone Present 7G' , 7G Most expressing cells located in subventricular zone and intermediate zone
TS26: cerebral cortex intermediate zone Present 7G , 7G' Most expressing cells located in subventricular zone and intermediate zone

Specimen 7H,H': embryonic day 18.5; Tg(Nes-cre)1Kln/0, Yap1tm1.1Dupa/Yap1tm1.1Dupa (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: cerebral cortex ventricular layer Weak 7H , 7H' Density of expressing cells similar to controls.
TS26: cerebral cortex subventricular zone Present 7H , 7H' Density of expressing cells similar to controls.
TS26: cerebral cortex intermediate zone Trace 7H' , 7H Density of expressing cells decreased compared to controls.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory