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Gene Expression Data
Assay Details
Assay
Reference: J:187631 Kredo-Russo S, et al., Pancreas-enriched miRNA refines endocrine cell differentiation. Development. 2012 Aug;139(16):3021-31
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7367247
Gene symbol: Ins1
Gene name: insulin I
Antibody: anti-insulin
Results
Specimen S1E: embryonic day 13.5 (more )
Note: Double labeled: green - Ins1 and Ins2; red - Mir7-1 (assay MGI:7367243) and Mir7-2 (assay MGI:7367273).
Structure Level Pattern Image Note
TS21: pancreas Present Regionally restricted S1E Co-expression with miR-7.

Specimen S1F: embryonic day 14.5 (more )
Note: Double labeled: green - Ins1 and Ins2; red - Mir7-1 (assay MGI:7367243) and Mir7-2 (assay MGI:7367273).
Structure Level Pattern Image Note
TS22: pancreas Present Regionally restricted S1F Co-expression with miR-7.

Specimen S1H: embryonic day 14.5 (more )
Note: Double labeled: green - Ins1 and Ins2; red - Mir375 (assay MGI:7367245).
Structure Level Pattern Image Note
TS22: pancreas Present Regionally restricted S1H Co-expression with mir375.

Specimen 1A: embryonic day 15.5 (more )
Note: Double labeled: green - Ins1 and Ins2; red - Mir7-1 (assay MGI:7367243) and Mir7-2 (assay MGI:7367273).
Structure Level Pattern Image Note
TS23: pancreas Present Regionally restricted 1A' Co-expression with miR-7.

Specimen 4L Pax6 WT: embryonic day 15.5 (more )
Note: Double labeled: green - Ins1 and Ins2; red - Gcg (assay MGI:7367252).
Structure Cell Type Level Pattern Image Note
TS23: pancreas type B pancreatic cell Present 4L Pax6 WT

Specimen 4L Pax6 Het: embryonic day 15.5; Pax6tm1Pgr/Pax6+ (more )
Note: Double labeled: green - Ins1 and Ins2; red - Gcg (assay MGI:7367252).
Structure Cell Type Level Pattern Image Note
TS23: pancreas type B pancreatic cell Weak 4L Pax6 Het Number of expressing beta cells reduced by 22% compared to wild type.

Specimen 5E Ctrl: embryonic day 15.5 (more )
Note: Double labeled: green - Ins1 and Ins2; red - Gcg (assay MGI:7367252).
Structure Cell Type Level Pattern Image Note
TS23: pancreas type B pancreatic cell Present 5E Ctrl


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory