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Gene Expression Data
Assay Details
Assay
Reference: J:187631 Kredo-Russo S, et al., Pancreas-enriched miRNA refines endocrine cell differentiation. Development. 2012 Aug;139(16):3021-31
Assay type: RNA in situ
MGI Accession ID: MGI:7367273
Gene symbol: Mir7-2
Gene name: microRNA 7-2
Probe: miR-7 probe2
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen S1B: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: pancreas epithelium Present Clusters S1B Expression in a subset of epithelial cells, clustered within compartment of developing pancreas.

Specimen S1E: embryonic day 13.5 (more )
Note: Double labeled: red - Mir7-1 and Mir7-2; green - Ins1 (assay MGI:7367247) and Ins2 (assay MGI:7367279).
Structure Cell Type Level Pattern Image Note
TS21: pancreas type B pancreatic cell Present Clusters S1E Expression in clustered cells, co-expressed with insulin.

Specimen S1F: embryonic day 14.5 (more )
Note: Double labeled: red - Mir7-1 and Mir7-2; green - Ins1 (assay MGI:7367247) and Ins2 (assay MGI:7367279).
Structure Cell Type Level Pattern Image Note
TS22: pancreas type B pancreatic cell Present Clusters S1F Expression in clustered cells, co-expressed with insulin.

Specimen S1G: embryonic day 12.5 (more )
Note: Double labeled: red - Mir7-1 and Mir7-2; white - Neurog3 (assay MGI:7367248).
Structure Cell Type Level Pattern Image Note
TS20: pancreas epithelium progenitor cell of endocrine pancreas Trace Clusters S1G Expression detected at very low levels as early as E12.5 in a defined set of clustered epithelial cells, some of which co-express Neurog3.

Specimen S1J: embryonic day 15.5 (more )
Note: Double labeled: red - Mir7-1 and Mir7-2; green - Ghrl (assay MGI:7367249).
Structure Level Pattern Image Note
TS23: pancreas Present Regionally restricted S1J Expression in Ghrl-expressing cells.

Specimen 1A,A': embryonic day 15.5 (more )
Note: Double labeled: red - Mir7-1 and Mir7-2; green - Ins1 (assay MGI:7367247) and Ins2 (assay MGI:7367279).
Structure Cell Type Level Pattern Image Note
TS23: pancreas type B pancreatic cell Present 1A , 1A'

Specimen 1A,A'': embryonic day 15.5 (more )
Note: Double labeled: red - Mir7-1 and Mir7-2; white - Gcg (assay MGI:7367252).
Structure Cell Type Level Pattern Image Note
TS23: pancreas pancreatic A cell Present 1A'' , 1A

Specimen 1B,B'': embryonic day 15.5 (more )
Note: Double labeled: red - Mir7-1 and Mir7-2; green - Cpa1 (assay MGI:7367253).
Structure Cell Type Level Pattern Image Note
TS23: pancreas pancreatic acinar cell Absent 1B , 1B'' No expression in differentiated acinar cells.

Specimen 1C,C',C'': embryonic day 14.5 (more )
Note: Double labeled: red - Mir7-1 and Mir7-2; green - Hnf1b (assay MGI:7367254).
Structure Cell Type Level Pattern Image Note
TS22: pancreas pancreatic ductal cell Absent 1C , 1C'' , 1C' No expression in differentiated duct cells.

Specimen 1D,D'': embryonic day 13.5 (more )
Note: Double labeled: red - Mir7-1 and Mir7-2; white - Neurog3 (assay MGI:7367248).
Structure Level Pattern Image Note
TS21: pancreas Present Regionally restricted 1D'' , 1D Co-expression in many Neurog3-expressing cells.

Specimen 1E,E'': embryonic day 14.5 (more )
Note: Double labeled: red - Mir7-1 and Mir7-2; white - Neurog3 (assay MGI:7367248).
Structure Level Pattern Image Note
TS22: pancreas Present Regionally restricted 1E , 1E'' Co-expression in many Neurog3-expressing cells.

Specimen 2E: embryonic day 15.5 (more )
Note: Double labeled: red - Mir7-1 and Mir7-2; green - Pax6 (assay MGI:7367256).
Structure Level Pattern Image Note
TS23: pancreas Present Regionally restricted 2E (merge) , 2E miR-7 Expression co-localized with Pax6.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory