Tg(Tek-CYP2C8)#Dcz
Transgene Detail
|
|
| Symbol: |
Tg(Tek-CYP2C8)#Dcz |
| Name: |
transgene insertion, Darryl Zeldin |
| MGI ID: |
MGI:7328772 |
| Synonyms: |
Tie2-CYP2C8-Tr |
| Transgene: |
Tg(Tek-CYP2C8)#Dcz Location: unknown
|
| Alliance: |
Tg(Tek-CYP2C8)#Dcz page
|
|
|
|
| Transgene Type: |
|
Transgenic (Inserted expressed sequence) |
| Mutation: |
|
Insertion
|
| |
|
Tg(Tek-CYP2C8)#Dcz expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
CYP2C8 (1558) |
|
|
|
| |
|
Mutation details: The human CYP2C8 (GenBank NM_000770) cDNA sequence was subcloned downstream of the murine Tek promoter and upstream of the Tek full enhancer sequences to drive endothelial expression in mice. Three lines were generated (lines 3, 7, and 8) but were not distinguished in data for the original reports. The pound # sign is used in the allele symbol where the line is not specified.
(J:165313)
|
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
| Original: |
J:165313 Lee CR, et al., Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice. FASEB J. 2010 Oct;24(10):3770-81 |
| All: |
10 reference(s) |
|
Analysis Tools
