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Gene Expression Data
Assay Details
Assay
Reference: J:326361 Li S, et al., Fate-mapping analysis of cochlear cells expressing Atoh1 mRNA via a new Atoh1(3*HA-P2A-Cre) knockin mouse strain. Dev Dyn. 2022 Jul;251(7):1156-1174
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7327507
Gene symbol: Myo6
Gene name: myosin VI
Antibody: anti-Myo6 (25-6791)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 2A': postnatal day 1; Atoh1em1(cre)Zyliu/Atoh1+ (more )
Note: Double labeled: green - Myo6; gray - Atoh1 reporter (assay MGI:7327506).
Structure Cell Type Level Pattern Image Note
TS27: cochlea cochlear inner hair cell Present 2A'
TS27: cochlea cochlear outer hair cell Present 2A'
Specimen 2B': postnatal day 1; Atoh1em1(cre)Zyliu/Atoh1+ (more )
Note: Double labeled: green - Myo6; gray - Atoh1 reporter (assay MGI:7327506).
Structure Cell Type Level Pattern Image Note
TS27: cochlea cochlear inner hair cell Present 2B
TS27: cochlea cochlear outer hair cell Present 2B
Specimen 2C': postnatal day 1; Atoh1em1(cre)Zyliu/Atoh1+ (more )
Note: Double labeled: green - Myo6; gray - Atoh1 reporter (assay MGI:7327506).
Structure Cell Type Level Pattern Image Note
TS27: cochlea cochlear inner hair cell Present
TS27: cochlea cochlear outer hair cell Present
Specimen 2D': postnatal day 1; Atoh1em1(cre)Zyliu/Atoh1+ (more )
Note: Triple labeled: green - Myo6; gray - Atoh1 reporter (assay MGI:7327506); red - Sox2 (assay MGI:7327508).
Structure Cell Type Level Pattern Image Note
TS27: cochlea cochlear inner hair cell Present 2D'
TS27: cochlea cochlear outer hair cell Present 2D'
Specimen 2E': postnatal day 5; Atoh1em1(cre)Zyliu/Atoh1+ (more )
Note: Double labeled: green - Myo6; gray - Atoh1 reporter (assay MGI:7327506).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present 2E'
TS28: cochlea cochlear outer hair cell Present 2E'
Specimen 2F': postnatal day 5; Atoh1em1(cre)Zyliu/Atoh1+ (more )
Note: Double labeled: green - Myo6; gray - Atoh1 reporter (assay MGI:7327506).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present 2F'
TS28: cochlea cochlear outer hair cell Present 2F'
Specimen 2G' OHC: postnatal day 5; Atoh1em1(cre)Zyliu/Atoh1+ (more )
Note: Double labeled: green - Myo6; gray - Atoh1 reporter (assay MGI:7327506).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear outer hair cell Present 2G' OHC
Specimen 2G' IHC: postnatal day 5; Atoh1em1(cre)Zyliu/Atoh1+ (more )
Note: Double labeled: green - Myo6; gray - Atoh1 reporter (assay MGI:7327506).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present 2G' IHC
Specimen 2H': postnatal day 5; Atoh1em1(cre)Zyliu/Atoh1+ (more )
Note: Triple labeled: green - Myo6; gray - Atoh1 reporter (assay MGI:7327506); red - Sox2 (assay MGI:7327508).
Structure Cell Type Level Pattern Image Note
TS28: cochlea cochlear inner hair cell Present 2H'
TS28: cochlea cochlear outer hair cell Present 2H'
Specimen 3A,A'': postnatal day 1; Atoh1em1(cre)Zyliu/Atoh1+ (more )
Note: Double labeled: green - Myo6; gray - Atoh1 reporter (assay MGI:7327506).
Structure Cell Type Level Pattern Image Note
TS27: utricle auditory hair cell Present 3A , 3A''
Specimen 3B,B'': postnatal day 5; Atoh1em1(cre)Zyliu/Atoh1+ (more )
Note: Double labeled: green - Myo6; gray - Atoh1 reporter (assay MGI:7327506).
Structure Level Pattern Image Note
TS28: crista ampullaris Present Regionally restricted 3B , 3B''
TS28: utricle Present Regionally restricted 3B , 3B''
Specimen 3C,C'': postnatal day 5; Atoh1em1(cre)Zyliu/Atoh1+ (more )
Note: Double labeled: green - Myo6; gray - Atoh1 reporter (assay MGI:7327506).
Structure Cell Type Level Pattern Image Note
TS28: utricle auditory hair cell Present 3C , 3C''
Specimen 3D,D'': postnatal day 15; Atoh1em1(cre)Zyliu/Atoh1+ (more )
Note: Double labeled: green - Myo6; gray - Atoh1 reporter (assay MGI:7327506).
Structure Cell Type Level Pattern Image Note
TS28: utricle auditory hair cell Present 3D'' , 3D
Specimen 5A,A''': embryonic day 12.5; Atoh1em1(cre)Zyliu/Atoh1+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Triple labeled: green - Myo6; gray - Atoh1 reporter (assay MGI:7327506); red - Cre reporter.
Structure Level Pattern Image Note
TS20: saccule Weak 5A''' , 5A
TS20: utricle Weak 5A''' , 5A
Specimen 5B,B''': embryonic day 12.5; Atoh1em1(cre)Zyliu/Atoh1+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Triple labeled: green - Myo6; gray - Atoh1 reporter (assay MGI:7327506); red - Cre reporter.
Structure Level Pattern Image Note
TS20: cochlea Ambiguous 5B''' , 5B
Specimen 5C: embryonic day 13.5; Atoh1em1(cre)Zyliu/Atoh1+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Triple labeled: green - Myo6; gray - Atoh1 reporter (assay MGI:7327506); red - Cre reporter.
Structure Level Pattern Image Note
TS21: saccule Present 5C
TS21: utricle Present 5C
Specimen 5D,D''': embryonic day 13.5; Atoh1em1(cre)Zyliu/Atoh1+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Triple labeled: green - Myo6; gray - Atoh1 reporter (assay MGI:7327506); red - Cre reporter.
Structure Cell Type Level Pattern Image Note
TS21: saccule auditory hair cell Strong 5D''' , 5D
TS21: saccule auditory epithelial supporting cell Absent 5D , 5D'''
Specimen 5E,E''': embryonic day 13.5; Atoh1em1(cre)Zyliu/Atoh1+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Triple labeled: green - Myo6; gray - Atoh1 reporter (assay MGI:7327506); red - Cre reporter.
Structure Cell Type Level Pattern Image Note
TS21: utricle auditory hair cell Strong 5E''' , 5E
TS21: utricle auditory epithelial supporting cell Absent 5E''' , 5E
Specimen 6A,A''': embryonic day 14.5; Atoh1em1(cre)Zyliu/Atoh1+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Triple labeled: green - Myo6; gray - Atoh1 reporter (assay MGI:7327506); red - Cre reporter.
Structure Level Pattern Image Note
TS22: cochlea Ambiguous 6A''' , 6A
Specimen 6B,B''': embryonic day 14.5; Atoh1em1(cre)Zyliu/Atoh1+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Triple labeled: green - Myo6; gray - Atoh1 reporter (assay MGI:7327506); red - Cre reporter.
Structure Level Pattern Image Note
TS22: cochlea Ambiguous 6B''' , 6B
Specimen 6C,C''': embryonic day 14.5; Atoh1em1(cre)Zyliu/Atoh1+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Triple labeled: green - Myo6; gray - Atoh1 reporter (assay MGI:7327506); red - Cre reporter.
Structure Level Pattern Image Note
TS22: cochlea Trace 6C , 6C'''
Specimen 6D,D''': embryonic day 14.5; Atoh1em1(cre)Zyliu/Atoh1+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Triple labeled: green - Myo6; gray - Atoh1 reporter (assay MGI:7327506); red - Cre reporter.
Structure Cell Type Level Pattern Image Note
TS22: cochlea cochlear inner hair cell Present Single cells 6D''' , 6D
TS22: cochlea cochlear outer hair cell Absent 6D , 6D'''
Specimen 7B,B''': embryonic day 15.5; Atoh1em1(cre)Zyliu/Atoh1+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Triple labeled: green - Myo6; gray - Atoh1 reporter (assay MGI:7327506); red - Cre reporter.
Structure Cell Type Level Pattern Image Note
TS23: cochlea cochlea auditory hair cell Ambiguous 7B''' , 7B
Specimen 7C,C''': embryonic day 15.5; Atoh1em1(cre)Zyliu/Atoh1+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Triple labeled: green - Myo6; gray - Atoh1 reporter (assay MGI:7327506); red - Cre reporter.
Structure Cell Type Level Pattern Image Note
TS23: cochlea cochlea auditory hair cell Present 7C''' , 7C
Specimen 7D,D''': embryonic day 15.5; Atoh1em1(cre)Zyliu/Atoh1+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Triple labeled: green - Myo6; gray - Atoh1 reporter (assay MGI:7327506); red - Cre reporter.
Structure Cell Type Level Pattern Image Note
TS23: cochlea cochlea auditory hair cell Present 7D''' , 7D
Specimen 7G: embryonic day 15.5; Atoh1em1(cre)Zyliu/Atoh1+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Triple labeled: green - Myo6; gray - Atoh1 reporter (assay MGI:7327506); red - Cre reporter.
Structure Level Pattern Image Note
TS23: cochlea Ambiguous 7G
Specimen 7H,H''': embryonic day 15.5; Atoh1em1(cre)Zyliu/Atoh1+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Triple labeled: green - Myo6; gray - Atoh1 reporter (assay MGI:7327506); red - Cre reporter.
Structure Level Pattern Image Note
TS23: cochlea Ambiguous 7H''' , 7H
Specimen 7I,I''': embryonic day 15.5; Atoh1em1(cre)Zyliu/Atoh1+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Triple labeled: green - Myo6; gray - Atoh1 reporter (assay MGI:7327506); red - Cre reporter.
Structure Level Pattern Image Note
TS23: cochlea Ambiguous 7I''' , 7I
Specimen 7J,J''': embryonic day 15.5; Atoh1em1(cre)Zyliu/Atoh1+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Triple labeled: green - Myo6; gray - Atoh1 reporter (assay MGI:7327506); red - Cre reporter.
Structure Level Pattern Image Note
TS23: cochlea Present Single cells 7J''' , 7J
Specimen 8G': postnatal day 1; Atoh1em1(cre)Zyliu/Atoh1+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Triple labeled: green - Myo6; gray - Sox2 (assay MGI:7327508); red - Cre reporter.
Structure Cell Type Level Pattern Image Note
TS27: organ of Corti cochlear inner hair cell Present 8G'
TS27: organ of Corti cochlear outer hair cell Present 8G'
TS27: organ of Corti Hensen cell Absent 8G'
Specimen 8H': postnatal day 1; Atoh1tm1(cre)Gan/Atoh1+, Gt(ROSA)26Sortm9(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Triple labeled: green - Myo6; gray - Sox2 (assay MGI:7327508); red - Cre reporter.
Structure Cell Type Level Pattern Image Note
TS27: organ of Corti cochlear inner hair cell Present 8H'
TS27: organ of Corti cochlear outer hair cell Present 8H'
TS27: organ of Corti Hensen cell Absent 8H'
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory