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Gene Expression Data
Assay Details
Assay
Reference: J:321982 De A, et al., The beta8 integrin cytoplasmic domain activates extracellular matrix adhesion to promote brain neurovascular development. Development. 2022 Mar 15;149(6):dev200472
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7282034
Gene symbol: Aif1
Gene name: allograft inflammatory factor 1
Antibody: anti-Iba1 (019-19741)
Detection system: Secondary antibody coupled to horseradish peroxidase
Assay notes: The antibody used in this assay was not specified; two antibodies were listed: MGI:5620494 and MGI:7281799.
Results
Specimen S8B: postnatal day 60 (more )
Structure Cell Type Level Pattern Image Note
TS28: cerebral cortex microglial cell Present S8B
Specimen S8D: postnatal day 60; Itgb8tm1Lfr/Itgb8tm1Lfr (more )
Structure Cell Type Level Pattern Image Note
TS28: cerebral cortex microglial cell Present S8D Increased numbers of microglial cells were noted in the mutant.
Specimen S8F: postnatal day 60; Tg(Nes-cre)1Kln/0 (more )
Structure Cell Type Level Pattern Image Note
TS28: cerebral cortex microglial cell Present S8F
Specimen S8H: postnatal day 60; Itgb8tm2Lfr/Itgb8tm2Lfr, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: cerebral cortex microglial cell Present S8H Increased numbers of microglial cells were noted in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory