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Gene Expression Data
Assay Details
Assay
Reference: J:260445 Wang C, et al., Centrosomal protein Dzip1l binds Cby, promotes ciliary bud formation, and acts redundantly with Bromi to regulate ciliogenesis in the mouse. Development. 2018 Mar 15;145(6):dev164236
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7281393
Gene symbol: Arl13b
Gene name: ADP-ribosylation factor-like 13B
Antibody: anti-Arl13b
Results
Specimen 2A WT NT: embryonic day 10.5 (more )
Note: Double labeled with acetylated tubulin (red).
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 2A WT NT Expression is in cilia of the neuroepithelia.
Specimen 2A Dzip1l-/- NT: embryonic day 10.5; Dzip1ltm1Blnw/Dzip1ltm1Blnw (more )
Note: Double labeled with acetylated tubulin (red).
Structure Level Pattern Image Note
TS17: neural tube Weak Regionally restricted 2A Dzip1l-/- NT In this mutant cilia density is reduced to 40% compared to wild-type.
Specimen 2A WT Limb: embryonic day 10.5 (more )
Note: Double labeled with acetylated tubulin (red).
Structure Level Pattern Image Note
TS17: limb mesenchyme Present Regionally restricted 2A WT Limb bud Expression is in cilia.
Specimen 2A Dzip1l-/- Limb: embryonic day 10.5; Dzip1ltm1Blnw/Dzip1ltm1Blnw (more )
Note: Double labeled with acetylated tubulin (red).
Structure Level Pattern Image Note
TS17: limb mesenchyme Weak Regionally restricted 2A Dzip1l-/- Limb bud In this mutant cilia density is reduced to 40% compared to wild-type.
Specimen 6A WT NT: embryonic day 10.5 (more )
Note: Double labeled with acetylated tubulin (red).
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 6A NT WT Expression is in cilia of the neuroepithelia.
Specimen 6A Dzip1l-/- NT: embryonic day 10.5; Dzip1ltm1Blnw/Dzip1ltm1Blnw (more )
Note: Double labeled with acetylated tubulin (red).
Structure Level Pattern Image Note
TS17: neural tube Present 6A NT Dzip1l-/- In this mutant cilia density is reduced to about half compared to wild-type.
Specimen 6A Bromi-/- NT: embryonic day 10.5; Tbc1d32tm1Blnw/Tbc1d32tm1Blnw (more )
Note: Double labeled with acetylated tubulin (red).
Structure Level Pattern Image Note
TS17: neural tube Present 6A NT Bromi-/- Expression in this mutant is similar to wild-type.
Specimen 6A Cby-/- NT: embryonic day 10.5; Cby1tm1Ktkm/Cby1tm1Ktkm (more )
Note: Double labeled with acetylated tubulin (red).
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 6A NT Cby-/- Expression in this mutant is similar to wild-type.
Specimen 6A Dzip1l-/-;Bromi-/- NT: embryonic day 10.5; Dzip1ltm1Blnw/Dzip1ltm1Blnw, Tbc1d32tm1Blnw/Tbc1d32tm1Blnw (more )
Note: Double labeled with acetylated tubulin (red).
Structure Level Pattern Image Note
TS17: neural tube Trace Regionally restricted 6A NT Dzip1l-/-;Bromi-/- In this mutant cilia density is scarce compared to wild-type.
Specimen 6A Dzip1l-/-;Cby-/- NT: embryonic day 10.5; Cby1tm1Ktkm/Cby1tm1Ktkm, Dzip1ltm1Blnw/Dzip1ltm1Blnw (more )
Note: Double labeled with acetylated tubulin (red).
Structure Level Pattern Image Note
TS17: neural tube Present Regionally restricted 6A NT Dzip1l-/-;Cby-/- In this mutant ilia density is reduced to about half compared to wild-type.
Specimen 6A WT LB: embryonic day 10.5 (more )
Note: Double labeled with acetylated tubulin (red).
Structure Level Pattern Image Note
TS17: limb mesenchyme Present Regionally restricted 6A LB WT Expression is in cilia.
Specimen 6A Bromi-/- LB: embryonic day 10.5; Tbc1d32tm1Blnw/Tbc1d32tm1Blnw (more )
Note: Double labeled with acetylated tubulin (red).
Structure Level Pattern Image Note
TS17: limb mesenchyme Present Regionally restricted 6A LB Bromi-/- Expression in this mutant is similar to wild-type.
Specimen 6A Dzip1l-/- LB: embryonic day 10.5; Dzip1ltm1Blnw/Dzip1ltm1Blnw (more )
Note: Double labeled with acetylated tubulin (red).
Structure Level Pattern Image Note
TS17: limb mesenchyme Present Regionally restricted 6A LB Dzip1l-/- In this mutant cilia density is reduced to about half compared to wild-type.
Specimen 6A Cby-/- LB: embryonic day 10.5; Cby1tm1Ktkm/Cby1tm1Ktkm (more )
Note: Double labeled with acetylated tubulin (red).
Structure Level Pattern Image Note
TS17: limb mesenchyme Present Regionally restricted 6A LB Cby-/- Expression in this mutant is similar to wild-type.
Specimen 6A Dzip1l-/-;Bromi-/- LB: embryonic day 10.5; Dzip1ltm1Blnw/Dzip1ltm1Blnw, Tbc1d32tm1Blnw/Tbc1d32tm1Blnw (more )
Note: Double labeled with acetylated tubulin (red).
Structure Level Pattern Image Note
TS17: limb mesenchyme Trace 6A LB Dzip1l-/-;Bromi-/- In this mutant cilia density is scarce compared to wild-type.
Specimen 6A Dzip1l-/-;Cby-/- LB: embryonic day 10.5; Cby1tm1Ktkm/Cby1tm1Ktkm, Dzip1ltm1Blnw/Dzip1ltm1Blnw (more )
Note: Double labeled with acetylated tubulin (red).
Structure Level Pattern Image Note
TS17: limb mesenchyme Present Regionally restricted 6A LB Dzip1l-/-;Cby-/- In this mutant ilia density is reduced to about half compared to wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory