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Gene Expression Data
Assay Details
Assay
Reference: J:308925 Chikada H, et al., Establishment and analysis of a mouse model that regulates sex-related differences in liver drug metabolism. Lab Invest. 2018 Nov;98(11):1500-1511
Assay type: RT-PCR
MGI Accession ID: MGI:7263329
Gene symbol: Esr1
Gene name: estrogen receptor 1 (alpha)
Probe: ERalpha-pG, ERalpha-pH
Assay notes: Quantitative RT-PCR. Relative expression was normalized to Hprt. Expression in male WT mouse livers was set to 1.0.
Results Image: 6b
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex Note
MWT P adult TS28: liver Present Not Specified; total RNA involves: C57BL/6 Male
FWT P adult TS28: liver Strong (a) Not Specified; total RNA involves: C57BL/6 Female
MLKO P adult TS28: liver Strong Not Specified; total RNA involves: C57BL/6 * DBA Bcl6tm1.1Mtto/Bcl6tm1.1Mtto, Speer6-ps1Tg(Alb-cre)21Mgn/0Male Conditional mutant.
FLKO P adult TS28: liver Strong Not Specified; total RNA involves: C57BL/6 * DBA Bcl6tm1.1Mtto/Bcl6tm1.1Mtto, Speer6-ps1Tg(Alb-cre)21Mgn/0Female Conditional mutant.
MWT P adult TS28: adipose tissue Present Not Specified; total RNA involves: C57BL/6 Male
FWT P adult TS28: adipose tissue Present Not Specified; total RNA involves: C57BL/6 Female
MLKO P adult TS28: adipose tissue Present (b) Not Specified; total RNA involves: C57BL/6 * DBA Bcl6tm1.1Mtto/Bcl6tm1.1Mtto, Speer6-ps1Tg(Alb-cre)21Mgn/0Male Conditional mutant.
MLKO P adult TS28: adipose tissue Present (b) Not Specified; total RNA involves: C57BL/6 * DBA Bcl6tm1.1Mtto/Bcl6tm1.1Mtto, Speer6-ps1Tg(Alb-cre)21Mgn/0Female Conditional mutant.
Notes:
(a) Expression in female livers was significantly higher than in male livers.
(b) Expression levels in this tissue is similar to controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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