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Gene Expression Data
Assay Details
Assay
Reference: J:316817 Guerra GM, et al., Cell Type-Specific Role of RNA Nuclease SMG6 in Neurogenesis. Cells. 2021 Nov 30;10(12)
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7260261
Gene symbol: Eomes
Gene name: eomesodermin
Antibody: anti-Eomes/Tbr2 (ab23345)
Detection system: Secondary antibody coupled to Cy2
Results
Specimen 1A Ctr: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebral cortex subventricular zone Present Regionally restricted 1A Ctr TBR2 Expression is in intermediate progenitors.
Specimen 1A CNSdelta: embryonic day 14.5; Smg6tm1.1Zqw/Smg6tm1.2Zqw, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: cerebral cortex subventricular zone Present 1A CNSdelta TBR2 Expression in this mutant is the same as in controls.
Specimen 1F Ctr: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex subventricular zone Present Regionally restricted 1F Ctr TBR2 Expression is in intermediate progenitors.
Specimen 1F CNSdelta: embryonic day 18.5; Smg6tm1.1Zqw/Smg6tm1.2Zqw, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: cerebral cortex subventricular zone Present Regionally restricted 1F CNSdelta TBR2 There is a significant decrease in the number of expressing cells in this mutant compared to controls.
Specimen 2A Ctr: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebral cortex subventricular zone Present Regionally restricted 2A Ctr Expression is in intermediate progenitors.
Specimen 2A CNSdelta: embryonic day 14.5; Smg6tm1.1Zqw/Smg6tm1.2Zqw, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: cerebral cortex subventricular zone Present Regionally restricted 2A CNSdelta right , 2A CNSdelta left
Specimen 2E Ctr: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex subventricular zone Present Regionally restricted 2E Ctrl Expression is in intermediate progenitors.
Specimen 2E CNSdelta: embryonic day 18.5; Smg6tm1.1Zqw/Smg6tm1.2Zqw, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: cerebral cortex subventricular zone Present Regionally restricted 2E CNSdelta right , 2E CNSdelta left
Specimen 4D Ctr: embryonic day 18.5 (more )
Note: Controls were littermates but their specific allelic background was not detailed.
Structure Level Pattern Image Note
TS26: cerebral cortex subventricular zone Present Regionally restricted 4D Ctr TBR2 Expression is in intermediate progenitors.
Specimen 4D CoHidelta: embryonic day 18.5; Emx1tm1(cre)Krj/Emx1+, Smg6tm1.1Zqw/Smg6tm1.1Zqw (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: cerebral cortex subventricular zone Present Regionally restricted 4D CoHidelta TBR2 Expression in this mutant is the same as in controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory