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Gene Expression Data
Assay Details
Assay
Reference: J:307192 Yadav PS, et al., Stat3 loss in mesenchymal progenitors causes Job syndrome-like skeletal defects by reducing Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2020100118
Assay type: RNA in situ
MGI Accession ID: MGI:6830999
Gene symbol: Mmp13
Gene name: matrix metallopeptidase 13
Probe: Mmp13 probe11
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2E E16.5 Prrx1Cre;Stat3C/+: embryonic day 16.5; Stat3tm1Flv/Stat3+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: humerus Present Regionally restricted 2E E16.5 Prrx1Cre;Stat3C/+ Expression is in the terminal hypertrophic chondrocytes/ osteoblasts.
Specimen 2E E16.5 Prrx1Cre;Stat3C/C: embryonic day 16.5; Stat3tm1Flv/Stat3tm1Flv, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: humerus Weak Regionally restricted 2E E16.5 Prrx1Cre;Stat3C/C
Specimen 3D Mmp13 OsxCre;Stat3C/+: embryonic day 16.5; Stat3tm1Flv/Stat3+, Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: humerus Present Regionally restricted 3D Mmp13 OsxCre;Stat3C/+ Expression is in the terminal hypertrophic chondrocytes/ osteoblasts.
Specimen 3D Mmp13 OsxCre;Stat3C/C: embryonic day 16.5; Stat3tm1Flv/Stat3tm1Flv, Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: humerus Weak Regionally restricted 3D Mmp13 OsxCre;Stat3C/C
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory