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Gene Expression Data
Assay Details
Assay
Reference: J:308106 Jang S, et al., Clmp Regulates AMPA and Kainate Receptor Responses in the Neonatal Hippocampal CA3 and Kainate Seizure Susceptibility in Mice. Front Synaptic Neurosci. 2020;12:567075
Assay type: RNA in situ
MGI Accession ID: MGI:6829691
Gene symbol: Clmp
Gene name: CXADR-like membrane protein
Probe: Mm-Clmp (542181)
Probe preparation: Antisense
Visualized with: Fluorescence
Assay notes: RNAscope assay using the C1 probe conjugated to Atto 550.
Results
Specimen 1C (upper): postnatal day 7 (more )
Note: Triple labeled: red - Clmp; green - Slc17a7 (assay MGI:6829693); white - Slc17a6 (assay MGI:6829694). Also stained with DAPI (blue).
Structure Level Pattern Image Note
TS28: brain Present Regionally restricted 1C Whole brain Merge (upper) , 1C Whole brain Clmp (upper) , 1C Whole brain (upper) Expression is seen in glutamatergic (and GABAergic) neurons.
TS28: cerebral cortex Present Regionally restricted 1C CC upper layer Clmp (upper) , 1C Whole brain (upper) , 1C CC upper layer Merge (upper) , 1C CC deep layer Merge (upper) , 1C CC deep layer Clmp (upper) Expression is seen in glutamatergic (and GABAergic) neurons of the upper and deep layers of the cerebral cortex.
TS28: hippocampus CA3 Present Regionally restricted 1C CA3 Merge (upper) , 1C CA3 Clmp (upper) , 1C Whole brain (upper) Expression is seen in glutamatergic (and GABAergic) neurons.
TS28: dentate gyrus Absent 1C DG Clmp (upper) , 1C DG Merge (upper) , 1C Whole brain (upper) At this age the authors reported expression as being "not abundant."
TS28: hippocampus CA1 Present Regionally restricted 1C CA1 Merge (upper) , 1C CA1 Clmp (upper) , 1C Whole brain (upper) Expression is seen in glutamatergic (and GABAergic) neurons.
Specimen 1C (lower): postnatal day 7 (more )
Note: Triple labeled: red - Clmp; green - Gad2 (assay MGI:6829695); white - Gad1 (assay MGI:6829696). Also stained with DAPI (blue).
Structure Level Pattern Image Note
TS28: brain Present 1C Whole brain Clmp (lower) , 1C Whole brain (lower) , 1C Whole brain Merge (lower) Expression is seen in GABAergic (and gluatamateric) neurons.
TS28: cerebral cortex Present 1C CC deep layer Merge (lower) , 1C CC deep layer Clmp (lower) , 1C Whole brain (lower) , 1C CC upper layer Clmp (lower) , 1C CC upper layer Merge (lower) Expression is seen in GABAergic (and gluatamateric) neurons of the upper and deep layers of the cerebral cortex.
TS28: hippocampus CA3 Present 1C Whole brain (lower) , 1C CA3 Merge (lower) , 1C CA3 Clmp (lower) Expression is seen in GABAergic (and gluatamateric) neurons.
TS28: dentate gyrus Absent 1C DG Merge (lower) , 1C DG Clmp (lower) , 1C Whole brain (lower) At this age the authors reported expression as being "not abundant."
TS28: hippocampus CA1 Present 1C Whole brain (lower) , 1C CA1 Clmp (lower) , 1C CA1 Merge (lower) Expression is seen in GABAergic (and gluatamateric) neurons.
Specimen 1D: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: hippocampus CA1 Strong 1D
TS28: hippocampus CA2 Strong 1D
TS28: hippocampus CA3 Strong 1D
TS28: dentate gyrus Absent 1D At this age the authors reported expression as being "not abundant."
Specimen 1E: postnatal day 56 (more )
Structure Level Pattern Image Note
TS28: hippocampus CA1 Strong 1E
TS28: hippocampus CA2 Strong 1E
TS28: hippocampus CA3 Strong 1E
TS28: dentate gyrus Strong 1E
Specimen S2A: postnatal day 56 (more )
Note: Triple labeled: red - Clmp; green - Slc17a7 (assay MGI:6829693); white - Slc17a6 (assay MGI:6829694). Also stained with DAPI (blue).
Structure Level Pattern Image Note
TS28: brain Present Regionally restricted S2A Whole brain , S2A Whole brain Merge , S2A Whole brain Clmp Expression is seen in glutamatergic (and GABAergic) neurons.
TS28: cerebral cortex Present Regionally restricted S2A CC lower layer Clmp , S2A CC upper layer Clmp , S2A CC lower layer Merge , S2A Whole brain , S2A CC upper layer Merge Expression is seen in glutamatergic (and GABAergic) neurons of the upper and deep layers of the cerebral cortex.
TS28: hippocampus CA3 Present Regionally restricted S2A CA3 Clmp , S2A Whole brain , S2A CA3 Merge Expression is seen in glutamatergic (and GABAergic) neurons.
TS28: dentate gyrus Present Regionally restricted S2A DG Clmp , S2A DG Merge , S2A Whole brain Expression is seen in glutamatergic (and GABAergic) neurons.
TS28: hippocampus CA1 Present Regionally restricted S2A CA1 Merge , S2A CA1 Clmp , S2A Whole brain Expression is seen in glutamatergic (and GABAergic) neurons.
Specimen S2B: postnatal day 56 (more )
Note: Triple labeled: red - Clmp; green - Gad2 (assay MGI:6829695); white - Gad1 (assay MGI:6829696). Also stained with DAPI (blue).
Structure Level Pattern Image Note
TS28: brain Present Regionally restricted S2B Whole brain Merge , S2B Whole brain , S2B Whole brain Clmp Expression is seen in GABAergic (and gluatamateric) neurons.
TS28: cerebral cortex Present Regionally restricted S2B CC upper layer Merge , S2B CC upper layer Clmp , S2B CC deep layer Clmp , S2B Whole brain , S2B CC deep layer Merge Expression is seen in GABAergic (and gluatamateric) neurons of the upper and deep layers of the cerebral cortex.
TS28: hippocampus CA3 Present Regionally restricted S2B CA3 Merge , S2B CA3 Clmp , S2B Whole brain Expression is seen in GABAergic (and gluatamateric) neurons.
TS28: dentate gyrus Present Regionally restricted S2B DG Clmp , S2B Whole brain , S2B DG Merge Expression is seen in GABAergic (and gluatamateric) neurons.
TS28: hippocampus CA1 Present Regionally restricted S2B CA1 Clmp , S2B CA1 Merge , S2B Whole brain Expression is seen in GABAergic (and gluatamateric) neurons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
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