Gene Expression Data
Assay Details
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Assay
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Reference:
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J:94639
Diep DB, et al., Characterisation of the Wnt antagonists and their response to conditionally activated Wnt signalling in the developing mouse forebrain. Brain Res Dev Brain Res. 2004 Nov 25;153(2):261-70
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6761305
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Gene symbol:
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Wif1
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Gene name:
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Wnt inhibitory factor 1
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Probe:
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Wif1 probe3
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
5C Wild-type Rostral:
embryonic day 13.5; Ctnnb1tm1Mmt/Ctnnb1 +
(more  )
Specimen
5C Wild-type Rostral:
(close  )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * SJL
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Mutant Allele(s):
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Ctnnb1tm1Mmt/Ctnnb1+
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: allocortex |
Present |
Regionally restricted |
5C Wild-type Rostral
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Expression in hippocampal and thalamic structures of medial wall.
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| TS21: thalamus |
Present |
Regionally restricted |
5C Wild-type Rostral
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Expression in hippocampal and thalamic structures of medial wall.
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Specimen
5C Wild-type Caudal:
embryonic day 13.5; Ctnnb1tm1Mmt/Ctnnb1 +
(more )
Specimen
5C Wild-type Caudal:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * SJL
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Mutant Allele(s):
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Ctnnb1tm1Mmt/Ctnnb1+
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: allocortex |
Present |
Regionally restricted |
5C Wild-type Caudal
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Expression in hippocampal and thalamic structures of medial wall.
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| TS21: thalamus |
Present |
Regionally restricted |
5C Wild-type Caudal
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Expression in hippocampal and thalamic structures of medial wall.
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Specimen
5C Wild-type Caudal inset:
embryonic day 13.5; Ctnnb1tm1Mmt/Ctnnb1 +
(more )
Specimen
5C Wild-type Caudal inset:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * SJL
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Mutant Allele(s):
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Ctnnb1tm1Mmt/Ctnnb1+
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: allocortex |
Present |
Regionally restricted |
5C Wild-type Caudal inset
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Expression in hippocampal epithelium just dorsal to cortical hem.
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| TS21: thalamus |
Present |
Regionally restricted |
5C Wild-type Caudal inset
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Expression in eminentia thalami.
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Specimen
5C Mutant Rostral:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * SJL
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Mutant Allele(s):
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Ctnnb1tm1Mmt/Ctnnb1+
Tg(Nes-cre)1Kln/0
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Conditional mutant.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: forebrain ventricular layer |
Present |
Widespread |
5C Mutant Rostral
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Expression over entire ventricular zone of forebrain.
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| TS21: allocortex |
Strong |
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5C Mutant Rostral
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Elevated expression in hippocampal and thalamic structures.
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| TS21: thalamus |
Strong |
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5C Mutant Rostral
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Elevated expression in hippocampal and thalamic structures.
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Specimen
5C Mutant Caudal:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * SJL
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Mutant Allele(s):
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Ctnnb1tm1Mmt/Ctnnb1+
Tg(Nes-cre)1Kln/0
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Conditional mutant.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: forebrain ventricular layer |
Present |
Widespread |
5C Mutant Caudal
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Expression over entire ventricular zone of forebrain.
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| TS21: telencephalon |
Present |
Graded |
5C Mutant Caudal
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Expression in a rostral-low and caudal-high gradient, particularly in basal ganglia.
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| TS21: allocortex |
Strong |
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5C Mutant Caudal
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Elevated expression in hippocampal and thalamic structures.
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| TS21: thalamus |
Strong |
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5C Mutant Caudal
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Elevated expression in hippocampal and thalamic structures.
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Specimen
6A M: wif1:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * SJL
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Mutant Allele(s):
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Ctnnb1tm1Mmt/Ctnnb1+
Tg(Nes-cre)1Kln/0
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Conditional mutant.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: forebrain |
Present |
Regionally restricted |
6A M: wif1
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Expression induced in midregion of medial wall.
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Specimen
6B M: wif1:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * SJL
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Mutant Allele(s):
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Ctnnb1tm1Mmt/Ctnnb1+
Tg(Nes-cre)1Kln/0
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Conditional mutant.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: forebrain |
Present |
Regionally restricted |
6B M: wif1
,
6B M: wif1 inset
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Expression induced in subventricular and/or ventricular zone.
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Specimen
6C M: wif1 (upper):
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * SJL
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Mutant Allele(s):
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Ctnnb1tm1Mmt/Ctnnb1+
Tg(Nes-cre)1Kln/0
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Conditional mutant.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: preoptic area |
Present |
Regionally restricted |
6C M: wif1 (upper)
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Expression induced in preoptic areas. Expression in broader and more continuous fashion along hypothalamus than seen for Dkk4.
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Specimen
6C M: wif1 (lower):
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * SJL
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Mutant Allele(s):
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Ctnnb1tm1Mmt/Ctnnb1+
Tg(Nes-cre)1Kln/0
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Conditional mutant.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: preoptic area |
Present |
Regionally restricted |
6C M: wif1 (lower)
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Expression induced in preoptic areas. Expression in broader and more continuous fashion along hypothalamus than seen for Dkk4.
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Specimen
6D M: wif1:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * SJL
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Mutant Allele(s):
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Ctnnb1tm1Mmt/Ctnnb1+
Tg(Nes-cre)1Kln/0
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Conditional mutant.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: allocortex |
Present |
Regionally restricted |
6D M: wif1
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Expression elevated in hippocampal CA fields and in thalamic tissues. No expression in anlage of dentate gyrus.
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| TS21: cortical hem |
Absent |
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6D M: wif1
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Analysis Tools