Gene Expression Data
Assay Details
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Assay
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Reference:
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J:94639
Diep DB, et al., Characterisation of the Wnt antagonists and their response to conditionally activated Wnt signalling in the developing mouse forebrain. Brain Res Dev Brain Res. 2004 Nov 25;153(2):261-70
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6761304
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Gene symbol:
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Dkk4
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Gene name:
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dickkopf WNT signaling pathway inhibitor 4
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Probe:
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Dkk4 probe2
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
E12 not shown:
embryonic day 12.0
(more  )
Specimen
E12 not shown:
(close  )
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Genetic Background:
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involves: C57BL/6 * CBA
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Age:
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embryonic day 12.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: forebrain |
Absent |
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No expression in forebrain at E12.
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Specimen
E12.5 not shown:
embryonic day 12.5
(more )
Specimen
E12.5 not shown:
(close )
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Genetic Background:
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involves: C57BL/6 * CBA
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: eye |
Absent |
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Little or no expression in eye at E12.5.
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Specimen
E15.5 not shown:
embryonic day 15.5
(more )
Specimen
E15.5 not shown:
(close )
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Genetic Background:
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involves: C57BL/6 * CBA
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: eye |
Absent |
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Little or no expression in eye at E15.5.
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Specimen
5B Wild-type Rostral:
embryonic day 13.5; Ctnnb1tm1Mmt/Ctnnb1 +
(more )
Specimen
5B Wild-type Rostral:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * SJL
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Mutant Allele(s):
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Ctnnb1tm1Mmt/Ctnnb1+
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: forebrain |
Ambiguous |
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5B Wild-type Rostral
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Authors do not describe expression.
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Specimen
5B Wild-type Caudal:
embryonic day 13.5; Ctnnb1tm1Mmt/Ctnnb1 +
(more )
Specimen
5B Wild-type Caudal:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * SJL
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Mutant Allele(s):
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Ctnnb1tm1Mmt/Ctnnb1+
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: forebrain |
Ambiguous |
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5B Wild-type Caudal
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Authors do not describe expression.
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Specimen
5B Mutant Rostral:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * SJL
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Mutant Allele(s):
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Ctnnb1tm1Mmt/Ctnnb1+
Tg(Nes-cre)1Kln/0
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Conditional mutant.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: forebrain |
Present |
Regionally restricted |
5B Mutant Rostral
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Highly regional induced expression, confined to midregion of medial wall.
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Specimen
5B Mutant Caudal:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * SJL
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Mutant Allele(s):
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Ctnnb1tm1Mmt/Ctnnb1+
Tg(Nes-cre)1Kln/0
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Conditional mutant.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: thalamus |
Present |
Regionally restricted |
5B Mutant Caudal
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Expression in eminentia thalami.
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Specimen
6A M: dkk4:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * SJL
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Mutant Allele(s):
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Ctnnb1tm1Mmt/Ctnnb1+
Tg(Nes-cre)1Kln/0
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Conditional mutant.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: forebrain |
Present |
Regionally restricted |
6A M: dkk4
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Expression induced in midregion of medial wall. Expression spread out over entire ventricular zone in a radial manner, with a predominance of ventricular side.
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Specimen
6B M: dkk4:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * SJL
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Mutant Allele(s):
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Ctnnb1tm1Mmt/Ctnnb1+
Tg(Nes-cre)1Kln/0
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Conditional mutant.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: ganglionic eminence |
Present |
Regionally restricted |
6B M: dkk4 inset
,
6B M: dkk4
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Expression induced in subventricular zone of ganglionic eminence.
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Specimen
6C W: dkk4:
embryonic day 13.5; Ctnnb1tm1Mmt/Ctnnb1 +
(more )
Specimen
6C W: dkk4:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * SJL
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Mutant Allele(s):
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Ctnnb1tm1Mmt/Ctnnb1+
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: preoptic area |
Ambiguous |
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6C W: dkk4
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Authors do not describe expression.
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Specimen
6C M: dkk4 (upper):
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * SJL
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Mutant Allele(s):
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Ctnnb1tm1Mmt/Ctnnb1+
Tg(Nes-cre)1Kln/0
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Conditional mutant.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: preoptic area |
Present |
Scattered |
6C M: dkk4 (upper)
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Expression induced in preoptic areas. Expression in a few scattered cells.
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Specimen
6C M: dkk4 (lower):
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * SJL
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Mutant Allele(s):
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Ctnnb1tm1Mmt/Ctnnb1+
Tg(Nes-cre)1Kln/0
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Conditional mutant.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: preoptic area |
Present |
Scattered |
6C M: dkk4 (lower)
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Expression induced in preoptic areas. Expression in a few scattered cells.
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Specimen
6D M: dkk4:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * SJL
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Mutant Allele(s):
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Ctnnb1tm1Mmt/Ctnnb1+
Tg(Nes-cre)1Kln/0
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Conditional mutant.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: forebrain |
Present |
Regionally restricted |
6D M: dkk4
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Highly regional induced expression, confined to midregion of medial wall.
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Analysis Tools