Gene Expression Data
Assay Details
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Assay
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Reference:
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J:94639
Diep DB, et al., Characterisation of the Wnt antagonists and their response to conditionally activated Wnt signalling in the developing mouse forebrain. Brain Res Dev Brain Res. 2004 Nov 25;153(2):261-70
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6761303
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Gene symbol:
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Dkk1
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Gene name:
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dickkopf WNT signaling pathway inhibitor 1
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Probe:
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Dkk1 probe10
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
E12 not shown:
embryonic day 12.0
(more  )
Specimen
E12 not shown:
(close  )
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Genetic Background:
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involves: C57BL/6 * CBA
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Age:
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embryonic day 12.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
1G:
embryonic day 15.5
(more )
Specimen
1G:
(close )
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Genetic Background:
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involves: C57BL/6 * CBA
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: hippocampus |
Present |
Regionally restricted |
1G
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Expression in hippocampal zone directly dorsal to fimbria.
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Specimen
1H:
embryonic day 15.5
(more )
Specimen
1H:
(close )
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Genetic Background:
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involves: C57BL/6 * CBA
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: hippocampus |
Present |
Regionally restricted |
1H
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Expression in hippocampal zone directly dorsal to fimbria.
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Specimen
4A:
embryonic day 12.5
(more )
Specimen
4A:
(close )
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Genetic Background:
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involves: C57BL/6 * CBA
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: eye epithelium |
Present |
Regionally restricted |
4A
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Expression at rim of lateral neuroepithelium, directly adjacent to overlying scleral mesenchyme.
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| TS20: eye |
Present |
Regionally restricted |
4A
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Expression in eyelid.
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Specimen
4D:
embryonic day 15.5
(more )
Specimen
4D:
(close )
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Genetic Background:
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involves: C57BL/6 * CBA
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: eye |
Absent |
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4D
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Specimen
P0 not shown:
postnatal day 0
(more )
Specimen
P0 not shown:
(close )
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Genetic Background:
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involves: C57BL/6 * CBA
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Age:
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postnatal day 0
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Specimen
5A Wild-type Rostral:
embryonic day 13.5; Ctnnb1tm1Mmt/Ctnnb1 +
(more )
Specimen
5A Wild-type Rostral:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * SJL
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Mutant Allele(s):
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Ctnnb1tm1Mmt/Ctnnb1+
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: forebrain |
Ambiguous |
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5A Wild-type Rostral
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Authors do not describe expression.
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Specimen
5A Wild-type Caudal:
embryonic day 13.5; Ctnnb1tm1Mmt/Ctnnb1 +
(more )
Specimen
5A Wild-type Caudal:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * SJL
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Mutant Allele(s):
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Ctnnb1tm1Mmt/Ctnnb1+
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: forebrain |
Ambiguous |
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5A Wild-type Caudal
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Authors do not describe expression.
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Specimen
5A Mutant Rostral:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * SJL
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Mutant Allele(s):
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Ctnnb1tm1Mmt/Ctnnb1+
Tg(Nes-cre)1Kln/0
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Conditional mutant.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: forebrain |
Present |
Widespread |
5A Mutant Rostral
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Expression broadly induced in entire forebrain of mutant.
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| TS21: cerebral cortex ventricular layer |
Present |
Widespread |
5A Mutant Rostral
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Expression throughout entire cortical ventricular zone, with a predominance to the outer layer of the ventricular zone.
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| TS21: cerebral cortex |
Present |
Regionally restricted |
5A Mutant Rostral
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Expression in radial columns that stretch from ventricular zone to mantle layer.
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Specimen
5A Mutant Caudal:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * SJL
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Mutant Allele(s):
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Ctnnb1tm1Mmt/Ctnnb1+
Tg(Nes-cre)1Kln/0
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Conditional mutant.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: allocortex |
Present |
Regionally restricted |
5A Mutant Caudal
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Expression in hippocampal and thalamic structures in medial wall.
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| TS21: thalamus |
Present |
Regionally restricted |
5A Mutant Caudal
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Expression in hippocampal and thalamic structures in medial wall.
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Specimen
6A M: dkk1:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * SJL
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Mutant Allele(s):
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Ctnnb1tm1Mmt/Ctnnb1+
Tg(Nes-cre)1Kln/0
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Conditional mutant.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: forebrain |
Present |
Regionally restricted |
6A M: dkk1
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Expression induced in midregion of medial wall.
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| TS21: forebrain ventricular layer |
Present |
Regionally restricted |
6A M: dkk1
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Most expressing cells along outer layer of ventricular zone.
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Specimen
6B M: dkk1:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * SJL
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Mutant Allele(s):
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Ctnnb1tm1Mmt/Ctnnb1+
Tg(Nes-cre)1Kln/0
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Conditional mutant.
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Specimen
6D M: dkk1:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * SJL
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Mutant Allele(s):
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Ctnnb1tm1Mmt/Ctnnb1+
Tg(Nes-cre)1Kln/0
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Conditional mutant.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: thalamus |
Present |
Regionally restricted |
6D M: dkk1
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Expression induced in anterior thalamus abutting eminencia thalami.
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| TS21: allocortex |
Present |
Regionally restricted |
6D M: dkk1
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Few expressing cells in hippocampal neuroepithelium.
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Specimen
6D M: dkk1 inset:
(close )
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Genetic Background:
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involves: 129X1/SvJ * C57BL/6 * SJL
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Mutant Allele(s):
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Ctnnb1tm1Mmt/Ctnnb1+
Tg(Nes-cre)1Kln/0
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Embedding:
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Cryosection
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Note:
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Conditional mutant.
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