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Gene Expression Data
Assay Details
Assay
Reference: J:278916 Maruyama K, et al., Isl1-expressing non-venous cell lineage contributes to cardiac lymphatic vessel development. Dev Biol. 2019 Aug 15;452(2):134-143
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6758992
Gene symbol: Prox1
Gene name: prospero homeobox 1
Antibody: anti-Prox1 (#11-002)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen S3A/B/C: embryonic day 17.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Isl1tm1(cre)Sev/Isl1+ (more )
Note: Conditional mutant. Ventral side. Triple labeled: blue - Prox1; red - Lyve1 (assay MGI:6758952); green - Cre reporter.
Structure Level Pattern Image Note
TS25: lymphatic vessel endothelium Present Regionally restricted S3C Prox1 , S3C merge , S3B , S3A Colocalized with Isl1+ lineage and Lyve1 around the outflow tract.
Specimen S3D/E: embryonic day 17.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Isl1tm1(cre)Sev/Isl1+ (more )
Note: Conditional mutant. Dorsal side. Triple labeled: blue - Prox1; red - Lyve1 (assay MGI:6758952); green - Cre reporter.
Structure Level Pattern Image Note
TS25: lymphatic vessel endothelium Present Regionally restricted S3E Prox1 , S3D , S3E merge Colocalized with Lyve1, not the Isl1+ lineage on the dorsal side of the heart.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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