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Gene Expression Data
Assay Details
Assay
Reference: J:177992 Nowell CS, et al., Foxn1 regulates lineage progression in cortical and medullary thymic epithelial cells but is dispensable for medullary sublineage divergence. PLoS Genet. 2011 Nov;7(11):e1002348
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6725790
Gene symbol: Cdr1
Gene name: cerebellar degeneration related antigen 1
Antibody: anti-CDR1
Results
Specimen 1H CDR1: postnatal week 6; Foxn1tm1.1Cbln/Foxn1+ (more )
Note: Double labeled: green - Cdr1; red - K14 (Krt14 assay MGI:6725792).
Structure Level Pattern Image Note
TS28: thymus cortex epithelium Present 1H CDR1/K14 , 1H CDR1 Expression in cortical thymic epithelial cells.
Specimen 3C CDR1: postnatal week 6; Foxn1tm1.1Cbln/Foxn1tm1.1Cbln (more )
Note: Double labeled: green - Cdr1; red - K14 (Krt14 assay MGI:6725792).
Structure Level Pattern Image Note
TS28: thymus cortex epithelium Ambiguous 3C CDR1/K14 , 3C CDR1 Expression severely dowregulated.
Specimen 3I -4OHT AIRE: postnatal week 4; Foxn1tm1.1Cbln/Foxn1tm1Tbo, Gt(ROSA)26Sortm2(cre/ERT2)Brn/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Specimens are from uninjected littermate controls. Double labeled: red - Cdr1; green - pan-cytokeratin.
Structure Level Pattern Image Note
TS28: thymus cortex epithelium Ambiguous 3I -4OHT CDR1 , 3I -4OHT CDR1/panK
Specimen 4B R/- CDR1: postnatal adult; Foxn1tm1.1Cbln/Foxn1tm1Tbo (more )
Note: Double labeled: green - Cdr1; red - K14 (Krt14 assay MGI:6725792).
Structure Level Pattern Image Note
TS28: thymus cortex epithelium Present Single cells 4B R/- K14/CDR1 Authors report expression in occasional cells.
TS28: thymus medulla epithelium Present Single cells 4B R/- K14/CDR1 Authors report expression in occasional cells.
Specimen 4B -/- CDR1: postnatal adult; Foxn1tm1Tbo/Foxn1tm1Tbo (more )
Note: Double labeled: green - Cdr1; red - K14 (Krt14 assay MGI:6725792).
Structure Level Pattern Image Note
TS28: thymus cortex epithelium Ambiguous 4B -/- K14/CDR1
TS28: thymus medulla epithelium Ambiguous 4B -/- K14/CDR1
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory