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Gene Expression Data
Assay Details
Assay
Reference: J:207611 Lange AW, et al., Sox17 is required for normal pulmonary vascular morphogenesis. Dev Biol. 2014 Mar 1;387(1):109-20
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6717450
Gene symbol: Emcn
Gene name: endomucin
Antibody: anti-endomucin
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 1A: embryonic day 12.5 (more )
Note: Double labeled: red - Emcn; green - Sox17 (assay MGI:6717404).
Structure Level Pattern Image Note
TS20: lung vascular element Present Regionally restricted 1A Expression became increasingly restricted to capillary and venous endothelial cells in mature vascular networks.
Specimen 1B: embryonic day 14.5 (more )
Note: Double labeled: red - Emcn; green - Sox17 (assay MGI:6717404).
Structure Level Pattern Image Note
TS22: lung vascular element Present Regionally restricted 1B Expression became increasingly restricted to capillary and venous endothelial cells in mature vascular networks.
Specimen 1C: embryonic day 18.5 (more )
Note: Double labeled: red - Emcn; green - Sox17 (assay MGI:6717404).
Structure Level Pattern Image Note
TS26: lung vascular element Present Regionally restricted 1C Expression became increasingly restricted to capillary and venous endothelial cells in mature vascular networks. Primarily detected to the peripheral microvasculature.
Specimen 1H/I: embryonic day 18.5 (more )
Note: Double labeled: red - Emcn; green - Sox17 (assay MGI:6717404).
Structure Level Pattern Image Note
TS26: lung vascular element Present Regionally restricted 1H , 1I Expression became increasingly restricted to capillary and venous endothelial cells in mature vascular networks. Primarily detected to the peripheral microvasculature.
Specimen 6D: postnatal week 2 (more )
Note: Double labeled: red - Emcn; green - Acta2 (assay MGI:6717427).
Structure Level Pattern Image Note
TS28: lung vascular element Present Regionally restricted 6D Expressed in endothelial cells comprising the pulmonary microvasculature.
Specimen 6E: postnatal week 2; Sox17tm1Jaw/Sox17tm1Jaw, Twist2tm1.1(cre)Dor/Twist2+ (more )
Note: Conditional mutant. Double labeled: red - Emcn; green - Acta2 (assay MGI:6717427).
Structure Level Pattern Image Note
TS28: lung vascular element Present Regionally restricted 6E Positive-stained microvasculature was reduced compared with the control.
Specimen 6F: postnatal week 2; Sox17tm1Jaw/Sox17tm1Jaw, Twist2tm1.1(cre)Dor/Twist2+ (more )
Note: Conditional mutant. Double labeled: red - Emcn; green - Acta2 (assay MGI:6717427).
Structure Level Pattern Image Note
TS28: lung vascular element Present Regionally restricted 6F Positive-stained microvasculature was reduced compared with the control.
Specimen 6G: postnatal week 2 (more )
Note: Double labeled: red - Emcn; green - Acta2 (assay MGI:6717427).
Structure Level Pattern Image Note
TS28: lung vascular element Present Regionally restricted 6G Expressed in endothelial cells comprising the pulmonary microvasculature.
Specimen 6H: postnatal week 2; Sox17tm1Jaw/Sox17tm1Jaw, Twist2tm1.1(cre)Dor/Twist2+ (more )
Note: Conditional mutant. Double labeled: red - Emcn; green - Acta2 (assay MGI:6717427).
Structure Level Pattern Image Note
TS28: lung vascular element Present Regionally restricted 6H Positive-stained microvasculature was reduced compared with the control.
Specimen 6I: postnatal week 2; Sox17tm1Jaw/Sox17tm1Jaw, Twist2tm1.1(cre)Dor/Twist2+ (more )
Note: Conditional mutant. Double labeled: red - Emcn; green - Acta2 (assay MGI:6717427).
Structure Level Pattern Image Note
TS28: lung vascular element Present Regionally restricted 6I Positive-stained microvasculature was reduced compared with the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory