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Gene Expression Data
Assay Details
Assay
Reference: J:181235 Liu L, et al., Ndrg2 expression in neurogenic germinal zones of embryonic and postnatal mouse brain. J Mol Histol. 2012 Feb;43(1):27-35
Assay type: RNA in situ
MGI Accession ID: MGI:6515732
Gene symbol: Ndrg2
Gene name: N-myc downstream regulated gene 2
Probe: Ndrg2 cDNA3
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: telencephalon Strong Regionally restricted 1A Expression is in the hippocampus primodium.
TS19: brain ventricular layer Strong 1A
TS19: diencephalon Present 1A
TS19: future spinal cord Present 1A
TS19: mesencephalic vesicle Present 1A
TS19: metencephalon Present 1A

Specimen 1C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: brain ventricular layer Present 1C

Specimen 1D: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: brain ventricular layer Present 1D

Specimen 2A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: telencephalon ventricular layer Strong Regionally restricted 2A Expression is in the neocortex.

Specimen 2B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: telencephalon ventricular layer Strong Regionally restricted 2B Expression is in the neocortex.

Specimen 2C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex ventricular layer Strong 2C
TS20: cerebral cortex marginal layer Weak 2C

Specimen 2D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebral cortex subventricular zone Strong 2D
TS22: cerebral cortex ventricular layer Strong 2D
TS22: cortical plate Moderate 2D
TS22: cerebral cortex intermediate zone Weak 2D
TS22: cerebral cortex marginal layer Weak 2D
TS22: cortical subplate Weak 2D

Specimen 2E: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cerebral cortex subventricular zone Strong 2E
TS24: cerebral cortex ventricular layer Strong 2E
TS24: cortical plate Moderate 2E
TS24: cerebral cortex intermediate zone Weak 2E
TS24: cerebral cortex marginal layer Weak 2E
TS24: cortical subplate Weak 2E

Specimen 2F: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cerebral cortex subventricular zone Strong 2F
TS26: cerebral cortex ventricular layer Strong 2F
TS26: cortical plate Moderate 2F
TS26: cerebral cortex marginal zone Weak 2F

Specimen 2G: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: cerebral cortex subventricular zone Weak 2G

Specimen 2H: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex subventricular zone Weak 2H
TS28: telencephalon Present Regionally restricted 2H Expressionm is strong in the lateral ventricle but is significantly downregulated in the cerebral cortex.

Specimen 2I: postnatal day 14 (more )
Structure Level Pattern Image Note
TS28: cerebral cortex subventricular zone Weak 2I
TS28: telencephalon Present Regionally restricted 2I Expressionm is strong in the lateral ventricle but is significantly downregulated in the cerebral cortex.

Specimen 3A: embryonic day 11.5 (more )
Note: In situ hybridization signals were pseudo-colored green. Double labeled with BrdU (red).
Structure Level Pattern Image Note
TS19: telencephalon ventricular layer Present Regionally restricted 3A , 3C'' , 3C , 3C' Expression is in the neocortex.

Specimen 3E: embryonic day 11.5 (more )
Note: In situ hybridization signals were pseudo-colored green. Double labeled: green - Ndrg2; red - Mki67 (assay MGI:6515746).
Structure Level Pattern Image Note
TS19: telencephalon ventricular layer Present Regionally restricted 3G' , 3G , 3E , 3G'' Expression is in the neocortex.

Specimen 3I: embryonic day 11.5 (more )
Note: In situ hybridization signals were pseudo-colored green. Double labeled: green - Ndrg2; red - Nes (assay MGI:6515747).
Structure Level Pattern Image Note
TS19: telencephalon ventricular layer Present Regionally restricted 3K' , 3K'' , 3I , 3K Expression is in the neocortex.

Specimen 4A: postnatal day 30 (more )
Note: In situ hybridization signals were pseudo-colored green. Double labeled with BrdU (red).
Structure Level Pattern Image Note
TS28: telencephalon subventricular zone Strong 4A/B , 4D , 4D'

Specimen 4F: postnatal day 30 (more )
Structure Level Pattern Image Note
TS28: telencephalon subventricular zone Strong 4F/G , 4I , 4I'

Specimen 4K: postnatal day 30 (more )
Note: In situ hybridization signals were pseudo-colored green. Double labeled with BrdU (red).
Structure Level Pattern Image Note
TS28: dentate gyrus subgranular zone Strong 4K/L , 4N , 4N'
TS28: dentate gyrus granule cell layer Moderate 4N , 4K/L , 4N'

Specimen 4P: postnatal day 30 (more )
Structure Level Pattern Image Note
TS28: dentate gyrus subgranular zone Strong 4S , 4P/Q , 4S'
TS28: dentate gyrus granule cell layer Moderate 4S' , 4S , 4P/Q

Specimen 5A: postnatal day 7 (more )
Note: In situ hybridization signals were pseudo-colored green. Double labeled with BrdU (red).
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Strong 5A , 5C , 5C'
TS28: cerebellum external granule cell layer Absent 5A , 5C' , 5C

Specimen 5D: embryonic day 16.5 (more )
Note: In situ hybridization signals were pseudo-colored green. Double labeled with BrdU (red).
Structure Level Pattern Image Note
TS24: retina inner nuclear layer Strong 5F' , 5D , 5F
TS24: retina outer nuclear layer Absent 5F' , 5F , 5D

Specimen 5G: embryonic day 14.5 (more )
Note: In situ hybridization signals were pseudo-colored green. Double labeled with BrdU (red).
Structure Level Pattern Image Note
TS22: spinal cord ventricular layer Present Regionally restricted 5I' , 5I , 5G Expression is ventral.

Specimen S1A: postnatal day 30 (more )
Note: In situ hybridization signals were pseudo-colored green. Double labeled: green - Ndrg2; red - Gfap (assay MGI:6682004).
Structure Level Pattern Image Note
TS28: telencephalon subventricular zone Strong S1D' , S1A/B , S1D

Specimen S1E: postnatal day 30 (more )
Note: In situ hybridization signals were pseudo-colored green. Double labeled: green - Ndrg2; red - Gfap (assay MGI:6682004).
Structure Level Pattern Image Note
TS28: dentate gyrus subgranular zone Strong S1H' , S1H , S1E/F
TS28: dentate gyrus granule cell layer Moderate S1H , S1H' , S1E/F


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory