About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:170393 Zhang Q, et al., Expression of doublecortin reveals articular chondrocyte lineage in mouse embryonic limbs. Genesis. 2011 Feb;49(2):75-82
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6515615
Gene symbol: Dcx
Gene name: doublecortin
Reporter: lacZ
Direct Detection
Results
Specimen 1a top row left: embryonic day 10.5; Dcxtm1Caw/Dcx+ (more )
Structure Level Pattern Image Note
TS17: brain Present 1a top row left
TS17: forelimb bud Present 1a top row left
TS17: future spinal cord Present 1a top row left
TS17: hindlimb bud Present 1a top row left

Specimen 1a top row center: embryonic day 10.5; Dcxtm1Caw/Dcx+ (more )
Structure Level Pattern Image Note
TS17: brain Present 1a top row center
TS17: forelimb bud Present 1a top row center
TS17: future spinal cord Present 1a top row center
TS17: hindlimb bud Present 1a top row center

Specimen 1a top row right: embryonic day 10.5; Dcxtm1Caw/Dcx+ (more )
Structure Level Pattern Image Note
TS17: brain Present 1a top row right
TS17: forelimb bud Present 1a top row right
TS17: future spinal cord Present 1a top row right
TS17: hindlimb bud Present 1a top row right

Specimen 1a middle row left: embryonic day 10.5; Dcxtm1Caw/Dcx+ (more )
Structure Level Pattern Image Note
TS17: brain Present 1a middle row left
TS17: forelimb bud Present 1a middle row left
TS17: future spinal cord Present 1a middle row left

Specimen 1a middle row center: embryonic day 10.5; Dcxtm1Caw/Dcx+ (more )
Structure Level Pattern Image Note
TS17: brain Present 1a middle row center
TS17: forelimb bud Present 1a middle row center
TS17: future spinal cord Present 1a middle row center
TS17: hindlimb bud Present 1a middle row center

Specimen 1a bottom row left: embryonic day 10.5; Dcxtm1Caw/Dcx+ (more )
Structure Level Pattern Image Note
TS17: brain Present 1a bottom row left
TS17: forelimb bud Present 1a bottom row left
TS17: future spinal cord Present 1a bottom row left
TS17: hindlimb bud Present 1a bottom row left

Specimen 1a bottom row center-right: embryonic day 10.5; Dcxtm1Caw/Dcx+ (more )
Structure Level Pattern Image Note
TS17: brain Present 1a bottom row center-right
TS17: forelimb bud Present 1a bottom row center-right
TS17: future spinal cord Present 1a bottom row center-right
TS17: hindlimb bud Present 1a bottom row center-right

Specimen 1a bottom row right: embryonic day 10.5; Dcxtm1Caw/Dcx+ (more )
Structure Level Pattern Image Note
TS17: brain Present 1a bottom row right
TS17: forelimb bud Present 1a bottom row right
TS17: future spinal cord Present 1a bottom row right
TS17: hindlimb bud Present 1a bottom row right

Specimen 3a: embryonic day 9.5; Dcxtm1Caw/Dcx+ (more )
Structure Level Pattern Image Note
TS15: forelimb bud Weak 3a

Specimen 3a": embryonic day 9.5; Dcxtm1Caw/Dcx+ (more )
Structure Level Pattern Image Note
TS15: forelimb bud mesenchyme Weak 3a"
TS15: forelimb bud ectoderm Absent 3a"

Specimen 3b: embryonic day 10.5; Dcxtm1Caw/Dcx+ (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present 3b

Specimen 3b': embryonic day 10.5; Dcxtm1Caw/Dcx+ (more )
Structure Level Pattern Image Note
TS17: forelimb bud Present 3b'

Specimen 3b": embryonic day 10.5; Dcxtm1Caw/Dcx+ (more )
Structure Level Pattern Image Note
TS17: hindlimb bud Present 3b"

Specimen 3c: embryonic day 11.5; Dcxtm1Caw/Dcx+ (more )
Structure Level Pattern Image Note
TS19: handplate mesenchyme Present Regionally restricted 3c No expression in a wedge of handplate below the apical ectodermal ridge.

Specimen 3c': embryonic day 11.5; Dcxtm1Caw/Dcx+ (more )
Structure Level Pattern Image Note
TS19: footplate mesenchyme Present Regionally restricted 3c' No expression in a wedge of footplate below the apical ectodermal ridge.

Specimen 3c": embryonic day 11.5; Dcxtm1Caw/Dcx+ (more )
Structure Level Pattern Image Note
TS19: footplate mesenchyme Present 3c" No expression in a wedge of footplate below the apical ectodermal ridge.

Specimen 3d: embryonic day 12.5; Dcxtm1Caw/Dcx+ (more )
Structure Level Pattern Image Note
TS20: forelimb pre-cartilage condensation Present 3d
TS20: forelimb digit mesenchyme Present Regionally restricted 3d Expression in digit rays.

Specimen 3d': embryonic day 12.5; Dcxtm1Caw/Dcx+ (more )
Structure Level Pattern Image Note
TS20: hindlimb pre-cartilage condensation Present 3d'
TS20: hindlimb digit mesenchyme Present Regionally restricted 3d' Expression in digit rays.

Specimen 3d": embryonic day 12.5; Dcxtm1Caw/Dcx+ (more )
Structure Level Pattern Image Note
TS20: hindlimb pre-cartilage condensation Present 3d"

Specimen 3e: embryonic day 13.5; Dcxtm1Caw/Dcx+ (more )
Structure Level Pattern Image Note
TS21: elbow joint primordium Present 3e Expression in joint interzone.
TS21: shoulder joint primordium Present 3e Expression in joint interzone.
TS21: hand joint primordium Present Regionally restricted 3e Expression in metacarpal and digit joint primordia.
TS21: forelimb cartilage condensation Weak Regionally restricted 3e Weak or absent expression in nonjoint part of anlagen.

Specimen 3e': embryonic day 13.5; Dcxtm1Caw/Dcx+ (more )
Structure Level Pattern Image Note
TS21: hindlimb joint primordium Present 3e' Expression in joint interzone.
TS21: hindlimb cartilage condensation Weak Regionally restricted 3e' Weak or absent expression in nonjoint part of anlagen.

Specimen 3e": embryonic day 13.5; Dcxtm1Caw/Dcx+ (more )
Structure Level Pattern Image Note
TS21: hand joint primordium Present 3e" Expression in joint interzone.
TS21: hand pre-cartilage condensation Weak Regionally restricted 3e" Weak or absent expression in nonjoint part of anlagen.

Specimen 3f: embryonic day 14.5; Dcxtm1Caw/Dcx+ (more )
Structure Level Pattern Image Note
TS22: hand joint Present Regionally restricted 3f Expression in metacarpal and digit joints.

Specimen 3f': embryonic day 14.5; Dcxtm1Caw/Dcx+ (more )
Structure Level Pattern Image Note
TS22: foot joint Present Regionally restricted 3f' Expression in metatarsal and digit joints.

Specimen 3f": embryonic day 14.5; Dcxtm1Caw/Dcx+ (more )
Structure Level Pattern Image Note
TS22: foot joint Present Regionally restricted 3f" Expression in digit joints.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory