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Gene Expression Data
Assay Details
Assay
Reference: J:100435 Currle DS, et al., Direct and indirect roles of CNS dorsal midline cells in choroid plexus epithelia formation. Development. 2005 Aug;132(15):3549-59
Assay type: RNA in situ
MGI Accession ID: MGI:6505896
Gene symbol: Ttr
Gene name: transthyretin
Probe: IMAGE clone 1078224
Probe preparation: Antisense RNA
Results
Specimen 5A: embryonic day 12.5; Gdf7tm2Tmj/Gdf7tm3(cre)Tmj (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: diencephalon Weak Regionally restricted 5A Markedly reduced expression in choroid plexus epithelial cells compared with the controls.

Specimen 5B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: diencephalon Present Regionally restricted 5B Expressed in the choroid plexus epithelial cells of the anterior diencephalic midline.

Specimen 5C: embryonic day 14.5; Gdf7tm2Tmj/Gdf7tm3(cre)Tmj (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: diencephalon Present Regionally restricted 5C Reduced expression in the choroid plexus epithelial cells of anterior diencephalic midline.

Specimen 5D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: diencephalon Present Regionally restricted 5D Expressed in the choroid plexus epithelial cells of anterior diencephalic midline.

Specimen 5I: embryonic day 12.5; Gdf7tm2Tmj/Gdf7tm3(cre)Tmj (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: hindbrain Present Regionally restricted 5I Reduced expression in the choroid plexus epithelial cells.

Specimen 5J: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hindbrain Present Regionally restricted 5J Expressed in the choroid plexus epithelial cells.

Specimen 5K: embryonic day 14.5; Gdf7tm2Tmj/Gdf7tm3(cre)Tmj (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: hindbrain Present Regionally restricted 5K Reduced expression in the choroid plexus epithelial cells.

Specimen 5L: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: hindbrain Present Regionally restricted 5L Expressed in the choroid plexus epithelial cells.

Specimen 6A: embryonic day 12.5; Gdf7tm2Tmj/Gdf7tm3(cre)Tmj (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: telencephalon Strong Regionally restricted 6A Expressed in the choroid plexus epithelial cells, same as in the control.

Specimen 6B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: telencephalon Strong Regionally restricted 6B Expressed in the choroid plexus epithelial cells.

Specimen 6C: embryonic day 12.5; Gdf7tm2Tmj/Gdf7tm3(cre)Tmj (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: diencephalon Weak Regionally restricted 6C Markedly reduced expression compared with the controls.
TS20: hindbrain Strong Regionally restricted 6C Expressed in the choroid plexus epithelial cells, same as in the control.

Specimen 6D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: diencephalon Strong Regionally restricted 6D Expressed in the choroid plexus epithelial cells.
TS20: hindbrain Strong Regionally restricted 6D Expressed in the choroid plexus epithelial cells.

Specimen 7A: embryonic day 11.5 (more )
Note: anterior region
Structure Level Pattern Image Note
TS19: telencephalon Present Regionally restricted 7A Expressed in the choroid plexus epithelial cells bilaterally, separated by the Ttr-negative choroid plaque.
TS19: diencephalon Absent 7A

Specimen 7B: embryonic day 11.5 (more )
Note: posterior region
Structure Level Pattern Image Note
TS19: telencephalon Present Regionally restricted 7B Expressed in the choroid plexus epithelial cells bilaterally.
TS19: diencephalon Absent 7B

Specimen 7C: embryonic day 12.5 (more )
Note: anterior region
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted 7C Expressed in the choroid plexus epithelial cells bilaterally.

Specimen 7D: embryonic day 12.5 (more )
Note: more anterior region
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted 7D Expressed in the choroid plexus epithelial cells bilaterally, separated by the Ttr-negative choroid plaque.

Specimen 7E: embryonic day 12.5 (more )
Note: more posterior region
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted 7E Expressed in the choroid plexus epithelial cells bilaterally, separated by the Ttr-negative choroid plaque.
TS20: diencephalon Present Regionally restricted 7E Expressed in the choroid plexus epithelial cells.

Specimen 7F: embryonic day 12.5 (more )
Note: posterior region
Structure Level Pattern Image Note
TS20: telencephalon Present Regionally restricted 7F Expressed in the choroid plexus epithelial cells bilaterally.
TS20: diencephalon Present Regionally restricted 7F Expressed in the choroid plexus epithelial cells.

Specimen 9A: embryonic day 12.5; Gdf7tm2Tmj/Gdf7+, Tmem163Tg(ACTB-cre)2Mrt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: hindbrain Absent 9A

Specimen 9B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hindbrain Present Regionally restricted 9B Expressed in the choroid plexus epithelial cells.

Specimen 9C: embryonic day 12.5; Gdf7tm2Tmj/Gdf7+, Tmem163Tg(ACTB-cre)2Mrt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: diencephalon Absent 9C
TS20: telencephalon Absent 9C

Specimen 9D: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: diencephalon Present Regionally restricted 9D Expressed in the choroid plexus epithelial cells.
TS20: telencephalon Present Regionally restricted 9D Expressed in the choroid plexus epithelial cells.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory