About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:297018 Matsumoto A, et al., Fbxw7beta resides in the endoplasmic reticulum membrane and protects cells from oxidative stress. Cancer Sci. 2011;102(4):749-55
Assay type: Western blot
MGI Accession ID: MGI:6501030
Gene symbol: Notch1
Gene name: notch 1
Antibody: anti-Notch1
Detection system: Secondary antibody
Results Image: 3d
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Size Not Specified (a) Genetic BackgroundMutant Allele(s)Sex Note
Fbxw7b+/- E14.5 TS22: brain Present Not Specified involves: 129P2/OlaHsd Fbxw7tm2.1Kei/Fbxw7+Not Specified
Fbxw7b-/- E14.5 TS22: brain Present Not Specified involves: 129P2/OlaHsd Fbxw7tm2.1Kei/Fbxw7tm2.1KeiNot Specified
Nestin-Cre/Fbxw7+/F E14.5 TS22: brain Present Not Specified involves: 129P2/OlaHsd * C57BL/6 * SJL Fbxw7tm1Kei/Fbxw7+, Tg(Nes-cre)1Kln/0Not Specified Conditional mutant.
Nestin-Cre/Fbxw7F/F E14.5 TS22: brain Present Present (b) involves: 129P2/OlaHsd * C57BL/6 * SJL Fbxw7tm1Kei/Fbxw7tm1Kei, Tg(Nes-cre)1Kln/0Not Specified Conditional mutant.
Notes:
(a) This row represents in the phosphorylated isoform.
(b) The phosphorylated isoform accumulates in this mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory