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Gene Expression Data
Assay Details
Assay
Reference: J:93051 Marques S, et al., The activity of the Nodal antagonist Cerl-2 in the mouse node is required for correct L/R body axis. Genes Dev. 2004 Oct 1;18(19):2342-7
Assay type: RNA in situ
MGI Accession ID: MGI:6488539
Gene symbol: Nodal
Gene name: nodal growth differentiation factor
Probe: Nodal probe35
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3A: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: node Present 3A
TS12: lateral plate mesoderm Present Regionally restricted 3A Expression in left lateral plate mesoderm.
Specimen 3B: embryonic day 8.0; Dand5tm1Belo/Dand5tm1Belo (more )
Structure Level Pattern Image Note
TS12: node Present 3B Expression in node remains unaffected.
TS12: lateral plate mesoderm Present Regionally restricted 3B Authors report normal expression in 40% of mutant embryos.
Specimen 3C: embryonic day 8.0; Dand5tm1Belo/Dand5tm1Belo (more )
Structure Level Pattern Image Note
TS12: node Present 3C Expression in node remains unaffected.
TS12: lateral plate mesoderm Present Regionally restricted 3C Expression is bilateral in 50% of mutant embryos
Specimen 3D: embryonic day 8.0; Dand5tm1Belo/Dand5tm1Belo (more )
Structure Level Pattern Image Note
TS12: node Present 3D Expression in node remains unaffected.
TS12: lateral plate mesoderm Present Regionally restricted 3D Right-sided expression in lateral plate mesoderm in 10% of mutant embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory