Dand5^tm1Belo
Targeted Allele Detail

Summary

• Symbol: Dand5^tm1Belo
• Name: DAN domain family member 5, BMP antagonist; targeted mutation 1, Jose Antonio Belo
• MGI ID: MGI:3056132
• Synonyms: cerl-2^-
• Gene: Dand5 Location: Chr8:85542034-85558894 bp, - strand Genetic Position: Chr8, 41.17 cM
• Alliance: Dand5^tm1Belo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:93051
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P/Ola

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The second exon was replaced with a lacZ cassette and a neomycin-resistance gene. In situ hybridization demonstrated that lacZ was expressed in heterozygotes. (J:93051)

Expression

In Mice Carrying this Mutation:	21 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dand5 Mutation: 15 strains or lines available

References

• Original: J:93051 Marques S, et al., The activity of the Nodal antagonist Cerl-2 in the mouse node is required for correct L/R body axis. Genes Dev. 2004 Oct 1;18(19):2342-7
• All: 6 reference(s)