Gene Expression Data
Assay Details
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Assay
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Reference:
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J:80726
Biben C, et al., NK-2 class homeobox genes and pharyngeal/oral patterning: Nkx2-3 is required for salivary gland and tooth morphogenesis. Int J Dev Biol. 2002;46(4):415-22
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:6477923
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Gene symbol:
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Nkx2-3
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Gene name:
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NK2 homeobox 3
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
3A:
embryonic day 10.0; Nkx2-3tm1Rph/Nkx2-3 +
(more  )
Specimen
3A:
(close  )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Nkx2-3tm1Rph/Nkx2-3+
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Age:
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embryonic day 10.0
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
3B:
embryonic day 10.0; Nkx2-3tm1Rph/Nkx2-3 +
(more )
Specimen
3B:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Nkx2-3tm1Rph/Nkx2-3+
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Age:
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embryonic day 10.0
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
3C:
embryonic day 10.0; Nkx2-3tm1Rph/Nkx2-3 +
(more )
Specimen
3C:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Nkx2-3tm1Rph/Nkx2-3+
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Age:
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embryonic day 10.0
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Specimen
3D:
embryonic day 13.5; Nkx2-3tm1Rph/Nkx2-3 +
(more )
Specimen
3D:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Nkx2-3tm1Rph/Nkx2-3+
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
3E:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Nkx2-3tm1Rph/Nkx2-3+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
3F:
(close )
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Genetic Background:
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involves: 129S1/Sv
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Mutant Allele(s):
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Nkx2-3tm1.1Rph/Nkx2-3+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
3G:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Nkx2-3tm1Rph/Nkx2-3+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: sublingual gland |
Present |
Regionally restricted |
3G
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Expression is in the nuclei of mucous acinar cell rosettes, absent in acini, neuronal cells, connective tissue fibroblasts, and vascular smooth muscle and endothelial cells.
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| TS28: sublingual duct |
Present |
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3G
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Specimen
3H:
(close )
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Genetic Background:
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involves: 129S1/Sv
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Mutant Allele(s):
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Nkx2-3tm1.1Rph/Nkx2-3+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section from whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
3I:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Nkx2-3tm1Rph/Nkx2-3+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Specimen
3J:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Nkx2-3tm1Rph/Nkx2-3+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: tongue epithelium |
Present |
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3J
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Expression is in nuclei of the post-mitotic differentiating epithelial layers.
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Specimen
3K:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Nkx2-3tm1Rph/Nkx2-3tm1Rph
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: tongue |
Present |
Regionally restricted |
3K
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Expression is in lingual salivary gland
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Specimen
4H:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Nkx2-3tm1Rph/Nkx2-3+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Specimen
4I:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Nkx2-3tm1Rph/Nkx2-3tm1Rph
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: sublingual gland |
Present |
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4I
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This mutant has large areas of LacZ-negative cells, with relatively fewer LacZ-positive cells poorly organised into acinar structures.
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Specimen
4J:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Nkx2-3tm1Rph/Nkx2-3+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Specimen
4K:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Nkx2-3tm1Rph/Nkx2-3tm1Rph
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: sublingual gland |
Present |
Regionally restricted |
4K
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This mutant has large areas of LacZ-negative cells, with relatively fewer LacZ-positive cells poorly organised into acinar structures.
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Specimen
not shown:
postnatal adult; Nkx2-3tm1Rph/Nkx2-3 +
(more )
Specimen
not shown:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Nkx2-3tm1Rph/Nkx2-3+
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Specimen
not shown E13.5:
embryonic day 13.5; Nkx2-3tm1Rph/Nkx2-3 +
(more )
Specimen
not shown E13.5:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6
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Mutant Allele(s):
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Nkx2-3tm1Rph/Nkx2-3+
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Analysis Tools