Tg(Vav1-Hottip)1Xumsa
Transgene Detail
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| Symbol: |
Tg(Vav1-Hottip)1Xumsa |
| Name: |
transgene insertion 1, Mingjiang Xu |
| MGI ID: |
MGI:6470977 |
| Synonyms: |
Hottip-Tg |
| Transgene: |
Tg(Vav1-Hottip)1Xumsa Location: unknown Genetic Position: Chr10, Syntenic
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| Alliance: |
Tg(Vav1-Hottip)1Xumsa page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutations: |
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Insertion, Intragenic deletion
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Tg(Vav1-Hottip)1Xumsa involves 1 genes/genome features (Cdh23)
View all
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Tg(Vav1-Hottip)1Xumsa expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Hottip (MGI:3642509) |
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Mutation details: The transgenic construct contains the complete coding region sequence of the mouse Hottip locus under the control of the vav 1 oncogene promoter/control regions (Vav1; from the HS321/45-vav vector). The transgene integrated into chromosome 10 (Chr10:60117191), within the intron between exon 3 and exon 4 of Cdh23 (cadherin 23 (otocadherin) ) gene.
(J:282668)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:282668 Luo H, et al., HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice. Cancer Cell. 2019 Dec 9;36(6):645-659.e8 |
| All: |
1 reference(s) |
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Analysis Tools
