Six2 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:285711 Sweat YY, et al., Six2 regulates Pax9 expression, palatogenesis and craniofacial bone formation. Dev Biol. 2020 Feb 15;458(2):246-256
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:6470639
Gene symbol:	Six2
Gene name:	sine oculis-related homeobox 2

Antibody:	anti-Six2 (11562-1-AP)
Detection system:	Secondary antibody

Results

2A ©

Specimen 2A: embryonic day 12.5 (more

)

Structure	Level	Pattern	Image	Note
TS20: palatal shelf mesenchyme	Strong		2A

2A' ©

Specimen 2A': embryonic day 12.5; Six2^{tm3(EGFP/cre/ERT2)Amc}/Six2^{tm3(EGFP/cre/ERT2)Amc} (more

)

Structure	Level	Pattern	Image	Note
TS20: palatal shelf mesenchyme	Absent		2A'

2B ©

Specimen 2B: embryonic day 13.5 (more

)

Structure	Level	Pattern	Image	Note
TS21: palatal shelf mesenchyme	Strong		2B

2B' ©

Specimen 2B': embryonic day 13.5; Six2^{tm3(EGFP/cre/ERT2)Amc}/Six2^{tm3(EGFP/cre/ERT2)Amc} (more

)

Structure	Level	Pattern	Image	Note
TS21: palatal shelf mesenchyme	Absent		2B'

2C ©

Specimen 2C: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: palatal shelf mesenchyme	Present		2C
TS22: primary palate mesenchyme	Present		2C

2C' ©

Specimen 2C': embryonic day 14.5; Six2^{tm3(EGFP/cre/ERT2)Amc}/Six2^{tm3(EGFP/cre/ERT2)Amc} (more

)

Structure	Level	Pattern	Image	Note
TS22: palatal shelf mesenchyme	Absent		2C'
TS22: primary palate mesenchyme	Absent		2C'

2D ©

Specimen 2D: embryonic day 15.5 (more

)

Structure	Level	Pattern	Image	Note
TS23: palatal shelf mesenchyme	Present		2D
TS23: primary palate mesenchyme	Present		2D

2D' ©

Specimen 2D': embryonic day 15.5; Six2^{tm3(EGFP/cre/ERT2)Amc}/Six2^{tm3(EGFP/cre/ERT2)Amc} (more

)

Structure	Level	Pattern	Image	Note
TS23: palatal shelf mesenchyme	Absent		2D'
TS23: primary palate mesenchyme	Absent		2D'

2E ©

Specimen 2E: embryonic day 16.5 (more

)

Structure	Level	Pattern	Image	Note
TS24: palate mesenchyme	Weak		2E

2E' ©

Specimen 2E': embryonic day 16.5; Six2^{tm3(EGFP/cre/ERT2)Amc}/Six2^{tm3(EGFP/cre/ERT2)Amc} (more

)

Structure	Level	Pattern	Image	Note
TS24: palate mesenchyme	Absent		2E'

S4A ©

Specimen S4A: embryonic day 14.5 (more

)
Note: Double labeled: green - Six2; red - Pax9 (assay MGI:6470763).

Structure	Level	Pattern	Image	Note
TS22: palatal shelf mesenchyme	Present		S4A
TS22: primary palate mesenchyme	Present		S4A

S4B ©

Specimen S4B: embryonic day 14.5; Six2^{tm3(EGFP/cre/ERT2)Amc}/Six2^{tm3(EGFP/cre/ERT2)Amc} (more

)
Note: Double labeled: green - Six2; red - Pax9 (assay MGI:6470763).

Structure	Level	Pattern	Image	Note
TS22: palatal shelf mesenchyme	Absent		S4B
TS22: primary palate mesenchyme	Absent		S4B

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/18/2025 MGI 6.24