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Gene Expression Data
Assay Details
Assay
Reference: J:208345 Almaidhan A, et al., Neural crest-specific deletion of Ldb1 leads to cleft secondary palate with impaired palatal shelf elevation. BMC Dev Biol. 2014;14:3
Assay type: RNA in situ
MGI Accession ID: MGI:6460333
Gene symbol: Wnt5a
Gene name: wingless-type MMTV integration site family, member 5A
Probe: Wnt5a probe23
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 6A: embryonic day 13.5; Ldb1tm1Lmgd/Ldb1tm2Lmgd (more )
Structure Level Pattern Image Note
TS21: palatal shelf Strong Regionally restricted 6A Expression is strong in the anterior palate but weak in the posterior palate.
Specimen 6B: embryonic day 13.5; Ldb1tm1Lmgd/Ldb1tm2Lmgd, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: palatal shelf Present Regionally restricted 6B This mutant has ectopic expression at the distal tip of the posterior palatal shelf.
Specimen 6C: embryonic day 13.5; Ldb1tm1Lmgd/Ldb1tm2Lmgd (more )
Structure Level Pattern Image Note
TS21: palatal shelf Strong Regionally restricted 6C Expression is strong in the anterior palate but weak in the posterior palate.
Specimen 6D: embryonic day 13.5; Ldb1tm1Lmgd/Ldb1tm2Lmgd, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: palatal shelf Present Regionally restricted 6D This mutant has ectopic expression at the distal tip of the posterior palatal shelf.
Specimen 6E: embryonic day 13.5; Ldb1tm1Lmgd/Ldb1tm2Lmgd (more )
Structure Level Pattern Image Note
TS21: palatal shelf Strong Regionally restricted 6E Expression is strong in the anterior palate but weak in the posterior palate.
Specimen 6F: embryonic day 13.5; Ldb1tm1Lmgd/Ldb1tm2Lmgd, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: palatal shelf Present Regionally restricted 6F This mutant has ectopic expression at the distal tip of the posterior palatal shelf.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory