Gene Expression Data
Assay Details
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Assay
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Reference:
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J:76173
Vitelli F, et al., Tbx1 mutation causes multiple cardiovascular defects and disrupts neural crest and cranial nerve migratory pathways. Hum Mol Genet. 2002 Apr 15;11(8):915-22
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Assay type:
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In situ reporter (knock in)
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MGI Accession ID:
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MGI:6459264
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Gene symbol:
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Tbx1
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Gene name:
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T-box 1
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Reporter:
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lacZ
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Direct Detection
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Results
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Specimen
1B:
embryonic day 10.5; Tbx1tm1Bld/Tbx1 +
(more  )
Specimen
1B:
(close  )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Tbx1tm1Bld/Tbx1+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
1C:
embryonic day 9.5; Tbx1tm1Bld/Tbx1 +
(more )
Specimen
1C:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Tbx1tm1Bld/Tbx1+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
1D:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Tbx1tm1Bld/Del(16Es2el-Ufd1l)217Bld
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: pharynx |
Present |
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1D
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Authors report pharynx is hypoplastic.
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Specimen
E8.0 not shown:
embryonic day 8.0; Tbx1tm1Bld/Tbx1 +
(more )
Specimen
E8.0 not shown:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Tbx1tm1Bld/Tbx1+
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Age:
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embryonic day 8.0
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Sex:
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Not Specified
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Type:
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Not Specified
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Specimen
2A:
embryonic day 9.5; Tbx1tm1Bld/Tbx1 +
(more )
Specimen
2A:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Tbx1tm1Bld/Tbx1+
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
2B:
embryonic day 10.5; Tbx1tm1Bld/Tbx1 +
(more )
Specimen
2B:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Tbx1tm1Bld/Tbx1+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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Paraformaldehyde
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Specimen
2C:
embryonic day 11.5; Tbx1tm1Bld/Tbx1 +
(more )
Specimen
2C:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Tbx1tm1Bld/Tbx1+
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
4A:
embryonic day 9.75; Tbx1tm1Bld/Tbx1 +
(more )
Specimen
4A:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Tbx1tm1Bld/Tbx1+
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Age:
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embryonic day 9.75
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
4B:
embryonic day 9.75; Tbx1tm1Bld/Tbx1 +
(more )
Specimen
4B:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Tbx1tm1Bld/Tbx1+
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Age:
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embryonic day 9.75
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
4C:
embryonic day 10.5; Tbx1tm1Bld/Tbx1 +
(more )
Specimen
4C:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Tbx1tm1Bld/Tbx1+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
4D:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Tbx1tm1Bld/Dp(16Dgcr14-Ufd1l)217Bld
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
4E:
embryonic day 10.5; Tbx1tm1Bld/Tbx1 +
(more )
Specimen
4E:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Tbx1tm1Bld/Tbx1+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
4F:
embryonic day 10.5; Tbx1tm1Bld/Tbx1 +
(more )
Specimen
4F:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Tbx1tm1Bld/Tbx1+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: blood vessel endothelium |
Present |
Regionally restricted |
4F
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Expression in cells at confluence of 4th arch artery with dorsal aorta in subpopulation of endothelial cells.
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Specimen
4G:
embryonic day 11.5; Tbx1tm1Bld/Tbx1 +
(more )
Specimen
4G:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Tbx1tm1Bld/Tbx1+
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: internal carotid artery |
Present |
Regionally restricted |
4G
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Expression in cells lining lumen of internal carotid artery.
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Specimen
4H:
embryonic day 11.5; Tbx1tm1Bld/Tbx1 +
(more )
Specimen
4H:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Tbx1tm1Bld/Tbx1+
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: internal carotid artery |
Present |
Regionally restricted |
4H
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Expression in cells lining lumen of internal carotid artery.
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Specimen
5D:
embryonic day 10.5; Tbx1tm1Bld/Tbx1 +
(more )
Specimen
5D:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Tbx1tm1Bld/Tbx1+
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
5E:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Tbx1tm1Bld/Del(16Es2el-Ufd1l)217Bld
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
5F:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Tbx1tm1Bld/Del(16Es2el-Ufd1l)217Bld
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Age:
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embryonic day 10.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS17: outflow tract |
Present |
Regionally restricted |
5F
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Expression in outflow myocardium near inner curvature of heart.
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Specimen
5H:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Tbx1tm1Bld/Del(16Es2el-Ufd1l)217Bld
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
5I:
embryonic day 9.5; Tbx1tm1Bld/Tbx1 +
(more )
Specimen
5I:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
|
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Mutant Allele(s):
|
Tbx1tm1Bld/Tbx1+
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Age:
|
embryonic day 9.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
5J:
embryonic day 9.5; Tbx1tm1Bld/Tbx1 +
(more )
Specimen
5J:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
|
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Mutant Allele(s):
|
Tbx1tm1Bld/Tbx1+
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Age:
|
embryonic day 9.5
|
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Sex:
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Not Specified
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Type:
|
section
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Fixation:
|
Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: outflow tract |
Present |
Regionally restricted |
5J
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Expression in cells in muscular wall of outflow tract.
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Specimen
5K:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Tbx1tm1Bld/Del(16Es2el-Ufd1l)217Bld
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
|
section
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Fixation:
|
Paraformaldehyde
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|
Embedding:
|
Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: outflow tract |
Present |
Regionally restricted |
5K
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Expression in cells in muscular wall of outflow tract.
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Specimen
5L:
embryonic day 11.5; Tbx1tm1Bld/Tbx1 +
(more )
Specimen
5L:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
|
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Mutant Allele(s):
|
Tbx1tm1Bld/Tbx1+
|
|
Age:
|
embryonic day 11.5
|
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Sex:
|
Not Specified
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Type:
|
section
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|
Fixation:
|
Paraformaldehyde
|
|
Embedding:
|
Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: outflow tract cardiac muscle |
Present |
Regionally restricted |
5L
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Expressing cells in outflow tract myocardium become more abundant later in developent.
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Specimen
5N:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Tbx1tm1Bld/Del(16Es2el-Ufd1l)217Bld
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Age:
|
embryonic day 11.5
|
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Sex:
|
Not Specified
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Type:
|
section
|
|
Fixation:
|
Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS19: outflow tract cardiac muscle |
Present |
Regionally restricted |
5N
|
Expressing cells in outflow tract myocardium become more abundant later in developent.
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Specimen
5P:
embryonic day 11.5; Tbx1tm1Bld/Tbx1 +
(more )
Specimen
5P:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
|
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Mutant Allele(s):
|
Tbx1tm1Bld/Tbx1+
|
|
Age:
|
embryonic day 11.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS19: outflow tract cardiac muscle |
Present |
Regionally restricted |
5P
|
Expressing cells in outflow tract myocardium become more abundant later in developent.
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Specimen
5R:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
|
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Mutant Allele(s):
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Tbx1tm1Bld/Del(16Es2el-Ufd1l)217Bld
|
|
Age:
|
embryonic day 11.5
|
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Sex:
|
Not Specified
|
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Type:
|
section
|
|
Fixation:
|
Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS19: outflow tract cardiac muscle |
Present |
Regionally restricted |
5R
|
Expressing cells in outflow tract myocardium become more abundant later in developent.
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Specimen
5T:
embryonic day 11.5; Tbx1tm1Bld/Tbx1 +
(more )
Specimen
5T:
(close )
|
Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
|
|
Mutant Allele(s):
|
Tbx1tm1Bld/Tbx1+
|
|
Age:
|
embryonic day 11.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS19: outflow tract endothelium |
Present |
Regionally restricted |
5T
|
Expression in endothelial and subendothelial cells in outflow tract.
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Specimen
5U:
embryonic day 12.5; Tbx1tm1Bld/Tbx1 +
(more )
Specimen
5U:
(close )
|
Genetic Background:
|
involves: 129S7/SvEvBrd * C57BL/6
|
|
Mutant Allele(s):
|
Tbx1tm1Bld/Tbx1+
|
|
Age:
|
embryonic day 12.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS20: ascending aorta |
Present |
Regionally restricted |
5U
|
Expression in cells along entire edge of pulmonary artery and aorta.
|
| TS20: pulmonary trunk |
Present |
Regionally restricted |
5U
|
Expression in cells along entire edge of pulmonary artery and aorta.
|
| TS20: outflow tract cardiac muscle |
Present |
Regionally restricted |
5U
|
Expression in group of cells in conal myocardium.
|
Specimen
5W:
embryonic day 12.5; Tbx1tm1Bld/Tbx1 +
(more )
Specimen
5W:
(close )
|
Genetic Background:
|
involves: 129S7/SvEvBrd * C57BL/6
|
|
Mutant Allele(s):
|
Tbx1tm1Bld/Tbx1+
|
|
Age:
|
embryonic day 12.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
Specimen
5X:
(close )
|
Genetic Background:
|
involves: 129S7/SvEvBrd * C57BL/6
|
|
Mutant Allele(s):
|
Tbx1tm1Bld/Del(16Es2el-Ufd1l)217Bld
|
|
Age:
|
embryonic day 12.5
|
|
Sex:
|
Not Specified
|
|
Type:
|
section
|
|
Fixation:
|
Paraformaldehyde
|
|
Embedding:
|
Paraffin
|
| Structure |
Level |
Pattern |
Image |
Note |
| TS20: outflow tract |
Present |
Regionally restricted |
5X
|
Expression in cells localized in wall of non-septated outlow tract.
|
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Analysis Tools