Dp(16Dgcr14-Ufd1l)217Bld
Targeted Allele Detail
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Symbol: |
Dp(16Dgcr14-Ufd1l)217Bld |
Name: |
duplication, Chr 16, Antonio Baldini 217 |
MGI ID: |
MGI:3640123 |
Synonyms: |
Dp1, Dp(16Dgcr14-Ufd1l)217Bld, dup(16)(Es2el-Ufd1l) |
Gene: |
Dp(16Dgcr14-Ufd1l)217Bld Location: unknown Genetic Position: Chr16, Syntenic
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Germline Transmission: |
Earliest citation of germline transmission:
J:57757
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Parent Cell Line: |
AB2.2 (ES Cell)
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Strain of Origin: |
129S7/SvEvBrd-Hprt1b-m2
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Allele Type: |
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Targeted (Null/knockout) |
Mutation: |
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Duplication
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Dp(16Dgcr14-Ufd1l)217Bld involves 42 genes/genome features (Gm26170, Gm15954, Gm26219 ...)
View all
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Mutation details: A proximal loxP site was targeted into the Es2el gene. The targeting vector replaced a 200-bp fragment containing exon 4. A second loxP site was targeted into the Ufd1l gene, replacing a 4.5-kb fragment containing exons 2-3. Transient expression of Cre resulted in recombination between loxP sites on opposite chromosomes duplicating the 1.2 MB region from Es2el to Ufd1l.
(J:57757)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Carrying any Dp(16Dgcr14-Ufd1l)217Bld Mutation: |
1 strain or line available
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Original: |
J:57757 Lindsay EA, et al., Congenital heart disease in mice deficient for the DiGeorge syndrome region [see comments]. Nature. 1999 Sep 23;401(6751):379-83 |
All: |
3 reference(s) |
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