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Gene Expression Data
Assay Details
Assay
Reference: J:278346 Winkler CC, et al., Loss of Shh signaling in the neocortex reveals heterogeneous cell recovery responses from distinct oligodendrocyte populations. Dev Biol. 2019 Aug 1;452(1):55-65
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6448410
Gene symbol: Sox10
Gene name: SRY (sex determining region Y)-box 10
Antibody: anti-Sox10
Detection system: Secondary antibody
Assay notes: These data are described in the text and summarized in table 1D and 1G.
Results
Specimen +/+: embryonic day 17.5; Emx1tm1(cre)Krj/Emx1+, Gt(ROSA)26Sortm1(CAG-lacZ,-EGFP)Glh/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Vibratome section.
Structure Level Pattern Image Note
TS25: neocortex region Present Regionally restricted Expression is in the somatosensory cortex.
Specimen fl/fl: embryonic day 17.5; Emx1tm1(cre)Krj/Emx1+, Gt(ROSA)26Sortm1(CAG-lacZ,-EGFP)Glh/Gt(ROSA)26Sor+, Smotm2Amc/Smotm2Amc (more )
Note: Conditional mutant. Vibratome section.
Structure Level Pattern Image Note
TS25: neocortex region Present Single cells The number of positive cells in the somatosensory cortex is significantly reduced in this mutant compared to controls.
Specimen +/+: postnatal day 30; Emx1tm1(cre)Krj/Emx1+, Gt(ROSA)26Sortm1(CAG-lacZ,-EGFP)Glh/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant. Vibratome section.
Structure Level Pattern Image Note
TS28: somatosensory cortex Present
Specimen fl/fl: postnatal day 30; Emx1tm1(cre)Krj/Emx1+, Gt(ROSA)26Sortm1(CAG-lacZ,-EGFP)Glh/Gt(ROSA)26Sor+, Smotm2Amc/Smotm2Amc (more )
Note: Conditional mutant. Vibratome section.
Structure Level Pattern Image Note
TS28: somatosensory cortex Present Expression is about 75% of that seen in controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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