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Gene Expression Data
Assay Details
Assay
Reference: J:193822 Lumayag S, et al., Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6444822
Gene symbol: Ctbp2
Gene name: C-terminal binding protein 2
Antibody: CtBP2 antibody Clone 16 (612044)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 7A: postnatal week 5 (more )
Structure Level Pattern Image Note
TS28: retina layer Present Regionally restricted 7A Expression was detected in a horseshoe-shaped pattern in photoreceptor termini.
Specimen 7B: postnatal week 5; Mirc35hgGt(D016D06)Wrst/Mirc35hgGt(D016D06)Wrst (more )
Structure Level Pattern Image Note
TS28: retina layer Present Regionally restricted 7B Staining became shorter and less defined, with dispersed immunoreactive puncta of variable size and less intensity in the mutant retina at 5 weeks.
Specimen 7C: postnatal year 1 (more )
Structure Level Pattern Image Note
TS28: retina layer Present Regionally restricted 7C Expression was detected in a horseshoe-shaped pattern in photoreceptor termini.
Specimen 7D: postnatal year 1; Mirc35hgGt(D016D06)Wrst/Mirc35hgGt(D016D06)Wrst (more )
Structure Level Pattern Image Note
TS28: retina layer Present Regionally restricted 7D The difference in staining in the mutant at 5 weeks became more striking in 1 year old animals.
Specimen 7E: postnatal week 5 (more )
Note: Double labeled: green - Ctbp2; red - peanut agglutinin.
Structure Level Pattern Image Note
TS28: retina layer Present Regionally restricted 7E Expression was detected in a horseshoe-shaped pattern in photoreceptor termini.
Specimen 7F: postnatal week 5; Mirc35hgGt(D016D06)Wrst/Mirc35hgGt(D016D06)Wrst (more )
Note: Double labeled: green - Ctbp2; red - peanut agglutinin.
Structure Level Pattern Image Note
TS28: retina layer Present Regionally restricted 7F Staining became shorter and less defined, with dispersed immunoreactive puncta of variable size and less intensity in the mutant retina at 5 weeks.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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