Mirc35hg^{Gt(D016D06)Wrst}
Gene trapped Allele Detail

Summary

• Symbol: Mirc35hg^{Gt(D016D06)Wrst}
• Name: microRNA cluster 35, host gene; gene trap D016D06, German Gene Trap Consortium
• MGI ID: MGI:3881348
• Synonyms: miR-183C^GT
• Gene: Mirc35hg Location: Chr6:30158639-30174124 bp, - strand Genetic Position: Chr6, Syntenic
• Alliance: Mirc35hg^{Gt(D016D06)Wrst} page

Small size of Mirc35hg^{Gt(D016D06)Wrst}/Mirc35hg^{Gt(D016D06)Wrst} mice

Show the 5 phenotype image(s) involving this allele.

Mutation origin

• Mutant Cell Line: D016D06
• Germline Transmission: Earliest citation of germline transmission: J:193822
• Parent Cell Line: TBV2 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: rFlpROSAbetageo
• Mutation details: The gene trap construct inserted into intron 1. RT-PCR confirmed the lack of expression of both alternatively spliced transcripts and all 3 mature miRNAs (Mir182, Mir96 and Mir183) in the retina of homozygous mice. (J:193822)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  D016D06	EI187871 ; (MGI Seq Detail)	5' RACE	Chr6:30173687-30173926 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  61 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Generation of the Mirc35hg^{Gt(D016D06)Wrst} allele

Expression

In Mice Carrying this Mutation:	348 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mirc35hg Mutation: 0 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 13 reference(s)