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Gene Expression Data
Assay Details
Assay
Reference: J:229352 Metzger DE, et al., Grg3/TLE3 and Grg1/TLE1 induce monohormonal pancreatic beta-cells while repressing alpha-cell functions. Diabetes. 2014 May;63(5):1804-16
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6441180
Gene symbol: Tle3
Gene name: transducin-like enhancer of split 3
Antibody: anti-Grg3
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 1B left: postnatal adult (more )
Note: Double labeled: gray - Tle3; green - Ins1 (assay MGI:6441182) and Ins2 (assay MGI:6441476).
Structure Level Pattern Image Note
TS28: islets of Langerhans Present 1B middle left , 1B left The majority of insulin-positive b-cells expressed Tle3. The percentage of Tle3+ beta-cells increased from E17.5 (84%) to the adult (98%).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory