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Gene Expression Data
Assay Details
Assay
Reference: J:36593 Wang Q, et al., The CBFbeta subunit is essential for CBFalpha2 (AML1) function in vivo. Cell. 1996 Nov 15;87(4):697-708
Assay type: RNA in situ
MGI Accession ID: MGI:6441055
Gene symbol: Cbfb
Gene name: core binding factor beta
Probe: CBFbeta p21.5 subclone
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2C +/+: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: cranial ganglion Present 2C +/+ (as)
TS19: dorsal root ganglion Present 2C +/+ (as)
TS19: telencephalon Present 2C +/+ (as)
TS19: liver Weak 2C +/+ (as) There is a fine, streaky pattern of expression.
Specimen 2C -/-: embryonic day 11.5; Cbfbtm1Spe/Cbfbtm1Spe (more )
Structure Level Pattern Image Note
TS19: cranial ganglion Present 2C -/- (as) Expression levels are lower in the mutant compared to wild type.
TS19: dorsal root ganglion Present 2C -/- (as) Expression levels are lower in the mutant compared to wild type.
TS19: liver Present 2C -/- (as) Expression levels are lower in the mutant compared to wild type.
TS19: telencephalon Present 2C -/- (as) Expression levels are lower in the mutant compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory