About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:257927 Fairchild CL, et al., RBX2 maintains final retinal cell position in a DAB1-dependent and -independent fashion. Development. 2018 Feb 2;145(3):dev155283
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6430438
Gene symbol: Dab1
Gene name: disabled 1
Antibody: Anti-Dab1 (HPA052033)
Assay notes: Two antibodies were described MGI:6430200 and MGI:6430189. The antibody used in this assay was not specified; either of these antibodies could have been used.
Results
Specimen 3D: postnatal day 15 (more )
Note: The genetic background of the conditional control specimen was not specified.
Structure Level Pattern Image Note
TS28: retina Present Regionally restricted 3D , 3D' Expression was detected in AII amacrine cells.
Specimen 3E: postnatal day 15; Rnf7tm1c(EUCOMM)Wtsi/Rnf7tm1c(EUCOMM)Wtsi, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: retina Present Regionally restricted 3E , 3E' In the conditional mutant, expression accumulated in the AII-amacrine cells and, most prominently, in the distal dendrites of these cells.
Specimen 3F: postnatal day 15 (more )
Note: The genetic background of the conditional control specimen was not specified.
Structure Level Pattern Image Note
TS28: lens epithelium Present 3F , 3F'
TS28: lens fiber Ambiguous 3F' , 3F
Specimen 3G: postnatal day 15; Rnf7tm1c(EUCOMM)Wtsi/Rnf7tm1c(EUCOMM)Wtsi, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: lens epithelium Present 3G' , 3G In the conditional mutant, Dab1 accumulated in the cytoplasm of the lens epithelium.
TS28: lens fiber Present 3G , 3G' In the conditional mutant, Dab1 accumulated in the nuclei of the secondary fibers of the lens.
Specimen 8C: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: retina Present Regionally restricted 8C , 8C' Expression was detected mainly in AII-amacrine cells.
Specimen 8D: postnatal day 15; Socs7tm1b(EUCOMM)Wtsi/Socs7tm1b(EUCOMM)Wtsi (more )
Structure Level Pattern Image Note
TS28: retina Present Regionally restricted 8D , 8D' Expression accumulated in AII-amacrine cells in the knockout mutant.
Specimen S3A: postnatal day 20 (more )
Note: The genetic background of the conditional control specimen was not specified.
Structure Level Pattern Image Note
TS28: retina Present S3A , S3A'
Specimen S3B: postnatal day 20; Rnf7tm1c(EUCOMM)Wtsi/Rnf7tm1c(EUCOMM)Wtsi, Tg(Crx-cre)352Gla/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: retina Present S3B' , S3B No Dab1 accumulation was observed in Rbx2cKO-Crx retinas.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory