About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:199301 Lavado A, et al., Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators. Development. 2013 Aug;140(16):3323-34
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6416278
Gene symbol: Lmx1a
Gene name: LIM homeobox transcription factor 1 alpha
Antibody: Anti-Lmx1a (C-17; sc-54273)
Assay notes: Two antibodies were described MGI:6407030 and MGI:6407084, but the one used in this assay was not specified. Either antibody could have been used.
Results
Specimen 2C: embryonic day 15.5 (more )
Note: The genetic background of the conditional control specimen was not specified.
Structure Level Pattern Image Note
TS23: telencephalon ventricular layer Present Regionally restricted 2C Expression was detected in the cortical hem.
Specimen 2D: embryonic day 15.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: telencephalon ventricular layer Present Regionally restricted 2D The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen not shown E14.5 control (2E): embryonic day 14.5 (more )
Note: The genetic background of the conditional control specimen was not specified.
Structure Level Pattern Image Note
TS22: telencephalon ventricular layer Present Regionally restricted Expression was detected in the cortical hem.
Specimen not shown E14.5 Nf2F/F;Emx1-Cre (2E): embryonic day 14.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: telencephalon ventricular layer Present Regionally restricted The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen not shown E16.5 control (2E): embryonic day 16.5 (more )
Note: The genetic background of the conditional control specimen was not specified.
Structure Level Pattern Image Note
TS24: telencephalon ventricular layer Present Regionally restricted Expression was detected in the cortical hem.
Specimen not shown E16.5 Nf2F/F;Emx1-Cre (2E): embryonic day 16.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: telencephalon ventricular layer Present Regionally restricted The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen 2F: embryonic day 15.5 (more )
Note: The genetic background of the conditional control specimen was not specified. Double labeled: magenta - Lmx1a; green - Mki67 (assay MGI:6416293).
Structure Level Pattern Image Note
TS23: telencephalon ventricular layer Present Regionally restricted 2F Expression was detected in the cortical hem.
Specimen 2G: embryonic day 15.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Double labeled: magenta - Lmx1a; green - Mki67 (assay MGI:6416293).
Structure Level Pattern Image Note
TS23: telencephalon ventricular layer Present Regionally restricted 2G The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen not shown E14.5 control (2H): embryonic day 14.5 (more )
Note: The genetic background of the conditional control specimen was not specified. Also stained for Mki67 (assay MGI:6416293).
Structure Level Pattern Image Note
TS22: telencephalon ventricular layer Present Regionally restricted Expression was detected in the cortical hem.
Specimen not shown E14.5 Nf2F/F;Emx1-Cre (2H): embryonic day 14.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Also stained for Mki67 (assay MGI:6416293).
Structure Level Pattern Image Note
TS22: telencephalon ventricular layer Present Regionally restricted The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen not shown E16.5 control (2H): embryonic day 16.5 (more )
Note: The genetic background of the conditional control specimen was not specified. Also stained for Mki67 (assay MGI:6416293).
Structure Level Pattern Image Note
TS24: telencephalon ventricular layer Present Regionally restricted Expression was detected in the cortical hem.
Specimen not shown E16.5 Nf2F/F;Emx1-Cre (2H): embryonic day 16.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Also stained for Mki67 (assay MGI:6416293).
Structure Level Pattern Image Note
TS24: telencephalon ventricular layer Present Regionally restricted The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen 3A': embryonic day 14.5 (more )
Note: The genetic background of the conditional control specimen was not specified. Double labeled: red - Lmx1a; green - Nes (assay MGI:6416317).
Structure Level Pattern Image Note
TS22: telencephalon ventricular layer Present Regionally restricted 3A' Expression was detected in the cortical hem.
Specimen 3B': embryonic day 16.5 (more )
Note: The genetic background of the conditional control specimen was not specified. Double labeled: red - Lmx1a; green - Nes (assay MGI:6416317).
Structure Level Pattern Image Note
TS24: telencephalon ventricular layer Present Regionally restricted 3B' Expression was detected in the cortical hem.
Specimen 3C': embryonic day 18.5 (more )
Note: The genetic background of the conditional control specimen was not specified. Double labeled: red - Lmx1a; green - Nes (assay MGI:6416317).
Structure Level Pattern Image Note
TS26: telencephalon ventricular layer Present Regionally restricted 3C' Expression was detected in the cortical hem.
Specimen 3D': embryonic day 14.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Double labeled: red - Lmx1a; green - Nes (assay MGI:6416317).
Structure Level Pattern Image Note
TS22: telencephalon ventricular layer Present Regionally restricted 3D' The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen 3E': embryonic day 16.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Double labeled: red - Lmx1a; green - Nes (assay MGI:6416317).
Structure Level Pattern Image Note
TS24: telencephalon ventricular layer Present Regionally restricted 3E' The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen 3F': embryonic day 18.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Double labeled: red - Lmx1a; green - Nes (assay MGI:6416317).
Structure Level Pattern Image Note
TS26: telencephalon ventricular layer Present Regionally restricted 3F' The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen 3G': embryonic day 14.5 (more )
Note: The genetic background of the conditional control specimen was not specified. Double labeled: red - Lmx1a; green - Fabp7 (assay MGI:6416318).
Structure Level Pattern Image Note
TS22: telencephalon ventricular layer Present Regionally restricted 3G' Expression was detected in the cortical hem.
Specimen 3H': embryonic day 15.5 (more )
Note: The genetic background of the conditional control specimen was not specified. Double labeled: red - Lmx1a; green - Fabp7 (assay MGI:6416318).
Structure Level Pattern Image Note
TS23: telencephalon ventricular layer Present Regionally restricted 3H' Expression was detected in the cortical hem.
Specimen 3I': embryonic day 16.5 (more )
Note: The genetic background of the conditional control specimen was not specified. Double labeled: red - Lmx1a; green - Fabp7 (assay MGI:6416318).
Structure Level Pattern Image Note
TS24: telencephalon ventricular layer Present Regionally restricted 3I' Expression was detected in the cortical hem.
Specimen 3J': embryonic day 14.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Double labeled: red - Lmx1a; green - Fabp7 (assay MGI:6416318).
Structure Level Pattern Image Note
TS22: telencephalon ventricular layer Present Regionally restricted 3J' The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen 3K': embryonic day 15.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Double labeled: red - Lmx1a; green - Fabp7 (assay MGI:6416318).
Structure Level Pattern Image Note
TS23: telencephalon ventricular layer Present Regionally restricted 3K' The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen 3L': embryonic day 16.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Double labeled: red - Lmx1a; green - Fabp7 (assay MGI:6416318).
Structure Level Pattern Image Note
TS24: telencephalon ventricular layer Present Regionally restricted 3L' The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen 4I: embryonic day 14.5 (more )
Note: The genetic background of the conditional control specimen was not specified. Double labeled: green - Lmx1a; red - Eomes (assay MGI:6416157).
Structure Level Pattern Image Note
TS22: telencephalon ventricular layer Present Regionally restricted 4I Expression was detected in the cortical hem.
Specimen 4J: embryonic day 14.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Double labeled: green - Lmx1a; red - Eomes (assay MGI:6416157).
Structure Level Pattern Image Note
TS22: telencephalon ventricular layer Present Regionally restricted 4J The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen 5A: embryonic day 14.5 (more )
Note: The genetic background of the conditional control specimen was not specified. Double labeled: green - Lmx1a; red - Trp73 (assay MGI:6416426).
Structure Level Pattern Image Note
TS22: telencephalon ventricular layer Present Regionally restricted 5A Expression was detected in the cortical hem.
Specimen 5B: embryonic day 14.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Double labeled: green - Lmx1a; red - Trp73 (assay MGI:6416426).
Structure Level Pattern Image Note
TS22: telencephalon ventricular layer Present Regionally restricted 5B The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen 5I: embryonic day 17.5 (more )
Note: The genetic background of the conditional control specimen was not specified. Double labeled: red - Lmx1a; green - Trp73 (assay MGI:6416426).
Structure Level Pattern Image Note
TS25: telencephalon ventricular layer Present Regionally restricted 5I Expression was detected in the cortical hem.
Specimen 5J: embryonic day 17.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Double labeled: red - Lmx1a; green - Trp73 (assay MGI:6416426).
Structure Level Pattern Image Note
TS25: telencephalon ventricular layer Present Regionally restricted 5J The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen 8A: embryonic day 15.5; Nf2tm2Gth/Nf2tm2Gth, Yap1tm1.1Eno/Yap1+, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: telencephalon ventricular layer Present Regionally restricted 8A The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen 8B: embryonic day 15.5; Nf2tm2Gth/Nf2tm2Gth, Yap1tm1.1Eno/Yap1tm1.1Eno, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: telencephalon ventricular layer Present Regionally restricted 8B The overgrowth of the cortical hem was significantly suppressed by the Yap1 mutation.
Specimen S2A': embryonic day 14.5 (more )
Note: The genetic background of the conditional control specimen was not specified.
Structure Level Pattern Image Note
TS22: telencephalon ventricular layer Present Regionally restricted S2A' Expression was detected in the cortical hem.
Specimen S2B': embryonic day 14.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: telencephalon ventricular layer Present Regionally restricted S2B' The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen S2C': embryonic day 15.5 (more )
Note: The genetic background of the conditional control specimen was not specified.
Structure Level Pattern Image Note
TS23: telencephalon ventricular layer Present Regionally restricted S2C' Expression was detected in the cortical hem.
Specimen S2D': embryonic day 15.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: telencephalon ventricular layer Present Regionally restricted S2D' The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen S2E': embryonic day 16.5 (more )
Note: The genetic background of the conditional control specimen was not specified.
Structure Level Pattern Image Note
TS24: telencephalon ventricular layer Present Regionally restricted S2E' Expression was detected in the cortical hem.
Specimen S2F': embryonic day 16.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: telencephalon ventricular layer Present Regionally restricted S2F' The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen S3A': embryonic day 14.5 (more )
Note: The genetic background of the conditional control specimen was not specified. Double labeled: red - Lmx1a; green - Pax6 (assay MGI:6416306).
Structure Level Pattern Image Note
TS22: telencephalon ventricular layer Present Regionally restricted S3A' Expression was detected in the cortical hem.
Specimen S3B': embryonic day 14.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Double labeled: red - Lmx1a; green - Pax6 (assay MGI:6416306).
Structure Level Pattern Image Note
TS22: telencephalon ventricular layer Present Regionally restricted S3B' The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen S3C': embryonic day 14.5 (more )
Note: The genetic background of the conditional control specimen was not specified. Double labeled: red - Lmx1a; green - Lhx2 (assay MGI:6416307).
Structure Level Pattern Image Note
TS22: telencephalon ventricular layer Present Regionally restricted S3C' Expression was detected in the cortical hem.
Specimen S3D': embryonic day 14.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Double labeled: red - Lmx1a; green - Lhx2 (assay MGI:6416307).
Structure Level Pattern Image Note
TS22: telencephalon ventricular layer Present Regionally restricted S3D' The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen S3E': embryonic day 16.5 (more )
Note: The genetic background of the conditional control specimen was not specified. Double labeled: red - Lmx1a; green - Pax6 (assay MGI:6416306).
Structure Level Pattern Image Note
TS24: telencephalon ventricular layer Present Regionally restricted S3E' Expression was detected in the cortical hem.
Specimen S3F': embryonic day 16.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Double labeled: red - Lmx1a; green - Pax6 (assay MGI:6416306).
Structure Level Pattern Image Note
TS24: telencephalon ventricular layer Present Regionally restricted S3F' The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen S3G': embryonic day 16.5 (more )
Note: The genetic background of the conditional control specimen was not specified. Double labeled: red - Lmx1a; green - Lhx2 (assay MGI:6416307).
Structure Level Pattern Image Note
TS24: telencephalon ventricular layer Present Regionally restricted S3G' Expression was detected in the cortical hem.
Specimen S3H': embryonic day 16.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Double labeled: red - Lmx1a; green - Lhx2 (assay MGI:6416307).
Structure Level Pattern Image Note
TS24: telencephalon ventricular layer Present Regionally restricted S3H' The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory