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Gene Expression Data
Assay Details
Assay
Reference: J:199301 Lavado A, et al., Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators. Development. 2013 Aug;140(16):3323-34
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6416293
Gene symbol: Mki67
Gene name: antigen identified by monoclonal antibody Ki 67
Results
Specimen 2F: embryonic day 15.5 (more )
Note: The genetic background of the conditional control specimen was not specified. Double labeled: green - Mki67; magenta - Lmx1a (assay MGI:6416278).
Structure Level Pattern Image Note
TS23: telencephalon ventricular layer Present Regionally restricted 2F Expression was detected in the cortical hem.
Specimen 2G: embryonic day 15.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Double labeled: green - Mki67; magenta - Lmx1a (assay MGI:6416278).
Structure Level Pattern Image Note
TS23: telencephalon ventricular layer Present Regionally restricted 2G The cortical hem was enlarged in the conditional mutant, and the percentage of Mki67 immunolabeled cells was increased at E15.5.
Specimen not shown E14.5 control (2H): embryonic day 14.5 (more )
Note: The genetic background of the conditional control specimen was not specified. Also stained for Lmx1a (assay MGI:6416278).
Structure Level Pattern Image Note
TS22: telencephalon ventricular layer Present Regionally restricted Expression was detected in the cortical hem.
Specimen not shown E14.5 Nf2F/F;Emx1-Cre (2H): embryonic day 14.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Also stained for Lmx1a (assay MGI:6416278).
Structure Level Pattern Image Note
TS22: telencephalon ventricular layer Present Regionally restricted The cortical hem was enlarged in the conditional mutant, and the percentage of Mki67 immunolabeled cells was increased at E14.5.
Specimen not shown E16.5 control (2H): embryonic day 16.5 (more )
Note: The genetic background of the conditional control specimen was not specified. Also stained for Lmx1a (assay MGI:6416278).
Structure Level Pattern Image Note
TS24: telencephalon ventricular layer Present Regionally restricted Expression was detected in the cortical hem.
Specimen not shown E16.5 Nf2F/F;Emx1-Cre (2H): embryonic day 16.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Also stained for Lmx1a (assay MGI:6416278).
Structure Level Pattern Image Note
TS24: telencephalon ventricular layer Present Regionally restricted Expression was detected in the cortical hem.
Specimen 2I: embryonic day 15.5 (more )
Note: The genetic background of the conditional control specimen was not specified. Double labeled: green - Mki67; red - BrdU.
Structure Level Pattern Image Note
TS23: telencephalon ventricular layer Present Regionally restricted 2I Expression was detected in the cortical hem.
Specimen 2J: embryonic day 15.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Double labeled: green - Mki67; red - BrdU.
Structure Level Pattern Image Note
TS23: telencephalon ventricular layer Present Regionally restricted 2J Twenty-four hours after BrdU pulse, the fraction of BrdU+ hem cells that were Mki67- (i.e. cells that exited the cell cycle within the 24-hour period) was decreased at E15.5.
Specimen not shown E14.5 control (2K): embryonic day 14.5 (more )
Note: The genetic background of the conditional control specimen was not specified. Double labeled: green - Mki67; red - BrdU.
Structure Level Pattern Image Note
TS22: telencephalon ventricular layer Present Regionally restricted Expression was detected in the cortical hem.
Specimen not shown E14.5 Nf2F/F;Emx1-Cre (2K): embryonic day 14.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Double labeled: green - Mki67; red - BrdU.
Structure Level Pattern Image Note
TS22: telencephalon ventricular layer Present Regionally restricted Twenty-four hours after BrdU pulse, the fraction of BrdU+ hem cells that were Mki67- (i.e. cells that exited the cell cycle within the 24-hour period) was decreased at E15.5.
Specimen not shown E16.5 control (2K): embryonic day 16.5 (more )
Note: The genetic background of the conditional control specimen was not specified. Double labeled: green - Mki67; red - BrdU.
Structure Level Pattern Image Note
TS24: telencephalon ventricular layer Present Regionally restricted Expression was detected in the cortical hem.
Specimen not shown E16.5 Nf2F/F;Emx1-Cre (2K): embryonic day 16.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Double labeled: green - Mki67; red - BrdU.
Structure Level Pattern Image Note
TS24: telencephalon ventricular layer Present Regionally restricted Expression was detected in the cortical hem.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
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