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Gene Expression Data
Assay Details
Assay
Reference: J:199301 Lavado A, et al., Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators. Development. 2013 Aug;140(16):3323-34
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6416306
Gene symbol: Pax6
Gene name: paired box 6
Results
Specimen S3A: embryonic day 14.5 (more )
Note: The genetic background of the conditional control specimen was not specified. Double labeled: green - Pax6; red - Lmx1a (assay MGI:6416278).
Structure Level Pattern Image Note
TS22: cerebral cortex Present S3A , S3A'
TS22: telencephalon Present Regionally restricted S3A , S3A' Expression was detected in the cortex, but was absent from the cortical hem.
Specimen S3B: embryonic day 14.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Lmx1a (assay MGI:6416278).
Structure Level Pattern Image Note
TS22: cerebral cortex Present S3B , S3B'
TS22: telencephalon Present Regionally restricted S3B' , S3B Expression was similar to controls, with expression in the cerebral cortex and low to undetectable levels in the hem.
Specimen S3E: embryonic day 16.5 (more )
Note: The genetic background of the conditional control specimen was not specified. Double labeled: green - Pax6; red - Lmx1a (assay MGI:6416278).
Structure Level Pattern Image Note
TS24: cerebral cortex Present S3E' , S3E
TS24: telencephalon Present Regionally restricted S3E , S3E' Expression was detected in the cortex, but was absent from the cortical hem.
Specimen S3F: embryonic day 16.5; Nf2tm2Gth/Nf2tm2Gth, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. Double labeled: green - Pax6; red - Lmx1a (assay MGI:6416278).
Structure Level Pattern Image Note
TS24: cerebral cortex Present S3F' , S3F
TS24: telencephalon Present Regionally restricted S3F , S3F' Expression was similar to controls, with expression in the cerebral cortex and low to undetectable levels in the hem.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory