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Gene Expression Data
Assay Details
Assay
Reference: J:150759 Lallemand Y, et al., Msx genes are important apoptosis effectors downstream of the Shh/Gli3 pathway in the limb. Dev Biol. 2009 Jul 15;331(2):189-98
Assay type: RNA in situ
MGI Accession ID: MGI:6404400
Gene symbol: Alx4
Gene name: aristaless-like homeobox 4
Results
Specimen 5E Forelimb Control: embryonic day 10.75 (more )
Structure Level Pattern Image Note
TS18: forelimb bud mesenchyme Present Regionally restricted 5E FL Control Expression marks anterior limb mesenchyme.
Specimen 5E Forelimb Shh-/-: embryonic day 10.75; Shhtm1Amc/Shhtm1Amc (more )
Structure Level Pattern Image Note
TS18: forelimb bud mesenchyme Strong Regionally restricted 5E FL Shh-/- Expression upregulated posteriorly.
Specimen 5E Forelimb Shh-/-Msx1-/-Msx2+/-: embryonic day 10.75; Msx1tm1Bero/Msx1tm1Bero, Msx2tm1Bero/Msx2+, Shhtm1Amc/Shhtm1Amc (more )
Structure Level Pattern Image Note
TS18: forelimb bud mesenchyme Strong Regionally restricted 5E FL Shh-/- Msx1-/- Msx2+/- Expression remains upregulated.
Specimen 5E Forelimb Shh-/-Msx1-/-Msx2-/-: embryonic day 10.75; Msx1tm1Bero/Msx1tm1Bero, Msx2tm1Bero/Msx2tm1Bero, Shhtm1Amc/Shhtm1Amc (more )
Structure Level Pattern Image Note
TS18: forelimb bud mesenchyme Strong Regionally restricted 5E FL Shh-/- Msx1-/- Msx2-/- Expression remains upregulated.
Specimen 5E Hindlimb Control: embryonic day 10.75 (more )
Structure Level Pattern Image Note
TS18: hindlimb bud mesenchyme Present Regionally restricted 5E HL Control Expression marks anterior limb mesenchyme.
Specimen 5E Hindlimb Shh-/-: embryonic day 10.75; Shhtm1Amc/Shhtm1Amc (more )
Structure Level Pattern Image Note
TS18: hindlimb bud mesenchyme Strong Regionally restricted 5E HL Shh-/- Expression upregulated posteriorly.
Specimen 5E Hindlimb Shh-/-Msx1-/-Msx2+/-: embryonic day 10.75; Msx1tm1Bero/Msx1tm1Bero, Msx2tm1Bero/Msx2+, Shhtm1Amc/Shhtm1Amc (more )
Structure Level Pattern Image Note
TS18: hindlimb bud mesenchyme Strong Regionally restricted 5E HL Shh-/- Msx1-/- Msx2+/- Expression remains upregulated.
Specimen 5E Hindlimb Shh-/-Msx1-/-Msx2-/-: embryonic day 10.75; Msx1tm1Bero/Msx1tm1Bero, Msx2tm1Bero/Msx2tm1Bero, Shhtm1Amc/Shhtm1Amc (more )
Structure Level Pattern Image Note
TS18: hindlimb bud mesenchyme Strong Regionally restricted 5E HL Shh-/- Msx1-/- Msx2-/- Expression remains upregulated.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory