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Gene Expression Data
Assay Details
Assay
Reference: J:228873 Stathopoulou A, et al., Inactivation of Geminin in neural crest cells affects the generation and maintenance of enteric progenitor cells, leading to enteric aganglionosis. Dev Biol. 2016 Jan 15;409(2):392-405
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6400299
Gene symbol: Ascl1
Gene name: achaete-scute family bHLH transcription factor 1
Antibody: anti-Mash1
Detection system: Alexa Fluor 568
Results
Specimen 5P/Q: embryonic day 9.5; Gmnntm1.1Kio/Gmnn+, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Double labeled: red - Ascl1; green - Cre reporter.
Structure Level Pattern Image Note
TS15: foregut Present Regionally restricted 5P/Q Expression in subset of enteric neural crest cells.
Specimen 5P'/Q': embryonic day 9.5; Gmnntm1.1Kio/Gmnntm1.1Kio, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Double labeled: red - Ascl1; green - Cre reporter.
Structure Level Pattern Image Note
TS15: foregut Weak Regionally restricted 5P'/Q' present / RR weak / RR present / RR weak / RR present / RR weak / RR present / RR weak / RR Expressing cells reduced 70% compared to control.
Specimen 5R/S: embryonic day 10.5; Gmnntm1.1Kio/Gmnn+, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Double labeled: red - Ascl1; green - Cre reporter.
Structure Level Pattern Image Note
TS17: foregut Present Regionally restricted 5R/S Expression in subset of enteric neural crest cells.
Specimen 5R'/S': embryonic day 10.5; Gmnntm1.1Kio/Gmnntm1.1Kio, Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant. Double labeled: red - Ascl1; green - Cre reporter.
Structure Level Pattern Image Note
TS17: foregut Weak Regionally restricted 5R'/S' Expressing cells reduced 76% compared to control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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01/06/2026
MGI 6.24 		The Jackson Laboratory