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Gene Expression Data
Assay Details
Assay
Reference: J:139188 Zhao H, et al., TGF-beta type I receptor Alk5 regulates tooth initiation and mandible patterning in a type II receptor-independent manner. Dev Biol. 2008 Aug 1;320(1):19-29
Assay type: RNA in situ
MGI Accession ID: MGI:6390877
Gene symbol: Lhx8
Gene name: LIM homeobox protein 8
Probe: Lhx7 probe1
Probe preparation: labelled with digoxigenin DNA
Results
Specimen 9E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch mandibular component mesenchyme Present 9E Expression in oral mesenchyme of maxilla and mandibular process.
TS17: 1st branchial arch maxillary component mesenchyme Present 9E Expression in oral mesenchyme of maxilla and mandibular process.

Specimen 9F: embryonic day 10.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: 1st branchial arch mandibular component mesenchyme Weak 9F Expression dramatically reduced at E10.5.
TS17: 1st branchial arch maxillary component mesenchyme Weak 9F Expression dramatically reduced at E10.5.

Specimen not shown: embryonic day 11.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: mandibular process mesenchyme Present Expression simlar to wild-type in both pattern and intensity.
TS19: maxillary process mesenchyme Present Expression simlar to wild-type in both pattern and intensity.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory