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Gene Expression Data
Assay Details
Assay
Reference: J:139188 Zhao H, et al., TGF-beta type I receptor Alk5 regulates tooth initiation and mandible patterning in a type II receptor-independent manner. Dev Biol. 2008 Aug 1;320(1):19-29
Assay type: RNA in situ
MGI Accession ID: MGI:6390872
Gene symbol: Msx1
Gene name: msh homeobox 1
Probe: Msx1 probe44
Probe preparation: labelled with digoxigenin DNA
Results
Specimen 8M: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch mandibular component Present 8M
TS17: 1st branchial arch maxillary component Present 8M
TS17: forebrain Present 8M
TS17: nasal process Present 8M
Specimen 8N: embryonic day 10.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: 1st branchial arch mandibular component Weak 8N Dramatically reduced expression in forebrain, nasal processes, maxilla processes and mandible processes.
TS17: 1st branchial arch maxillary component Weak 8N Dramatically reduced expression in forebrain, nasal processes, maxilla processes and mandible processes.
TS17: forebrain Weak 8N Dramatically reduced expression in forebrain, nasal processes, maxilla processes and mandible processes.
TS17: nasal process Weak 8N Dramatically reduced expression in forebrain, nasal processes, maxilla processes and mandible processes.
Specimen E9.5 not shown: embryonic day 9.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: 1st branchial arch mandibular component Weak Authors report reduced expression at E9.5.
TS15: 1st branchial arch maxillary component Weak Authors report reduced expression at E9.5.
Specimen E11.5 not shown: embryonic day 11.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: mandibular process Present No reduction of expression at E11.5.
TS19: maxillary process Present No reduction of expression at E11.5.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory