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Gene Expression Data
Assay Details
Assay
Reference: J:139188 Zhao H, et al., TGF-beta type I receptor Alk5 regulates tooth initiation and mandible patterning in a type II receptor-independent manner. Dev Biol. 2008 Aug 1;320(1):19-29
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6390860
Gene symbol: Shh
Gene name: sonic hedgehog
Antibody: anti-Shh
Results
Specimen 3A: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: enamel knot Present Regionally restricted 3A Expression upregulated in enamel knot.
TS23: incisor Present Regionally restricted 3A Expression upregulated in enamel knot.
Specimen 3B: embryonic day 15.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: incisor Absent 3B
Specimen 3C: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: enamel knot Present Regionally restricted 3C Expression upregulated in enamel knot.
TS23: molar Present Regionally restricted 3C Expression upregulated in enamel knot.
Specimen 3D: embryonic day 15.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: molar Absent 3D
Specimen 3E: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: incisor enamel organ Present Regionally restricted 3E Expression highly localized in enamel forming regions.
Specimen 3F: embryonic day 17.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS25: incisor Present Regionally restricted 3F Expression localized to tooth germs.
Specimen 3G: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: molar enamel organ Present Regionally restricted 3G Expression highly localized in enamel forming regions.
Specimen 3H: embryonic day 17.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS25: molar Present Regionally restricted 3H Expression localized to tooth germs.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory