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Gene Expression Data
Assay Details
Assay
Reference: J:139188 Zhao H, et al., TGF-beta type I receptor Alk5 regulates tooth initiation and mandible patterning in a type II receptor-independent manner. Dev Biol. 2008 Aug 1;320(1):19-29
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6390858
Gene symbol: Tgfbr1
Gene name: transforming growth factor, beta receptor I
Antibody: anti-ALK5
Results
Specimen S1A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: dental placode Present S1A
TS20: jaw primordium mesenchyme Present S1A
Specimen S1B: embryonic day 12.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: jaw primordium epithelium Present S1B
TS20: jaw primordium mesenchyme Absent S1B
Specimen S1C: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: incisor epithelium Present S1C
TS23: incisor mesenchyme Present S1C
Specimen S1D: embryonic day 15.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: incisor epithelium Present S1D
TS23: incisor mesenchyme Absent S1D
Specimen S1E: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: molar epithelium Present S1E
TS23: molar mesenchyme Present S1E
Specimen S1F: embryonic day 15.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS23: molar epithelium Present S1F
TS23: molar mesenchyme Absent S1F
Specimen S2A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: dental placode Present S2A
TS20: jaw primordium mesenchyme Present S2A
Specimen S2B: embryonic day 12.5; Tgfbr1tm1.1Karl/Tgfbr1tm1.1Karl, Tgfbr2tm1.2Hlm/Tgfbr2tm1.2Hlm, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: jaw primordium epithelium Present S2B
TS20: jaw primordium mesenchyme Absent S2B
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory