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Gene Expression Data
Assay Details
Assay
Reference: J:136711 Zhao H, et al., Fibroblast growth factor receptor signaling is essential for lens fiber cell differentiation. Dev Biol. 2008 Jun 15;318(2):276-88
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6386986
Gene symbol: Ccnd1
Gene name: cyclin D1
Results
Specimen 4A: embryonic day 12.5; Fgfr1tm1Jpa/Fgfr1tm1Jpa, Fgfr2tm1Dor/Fgfr2tm1Dor, Fgfr3tm1Dor/Fgfr3tm1Dor, Tg(Cryaa-cre)10Mlr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS21: lens Present Uniform 4A Expression unformly distributed.
Specimen 4B: embryonic day 12.5; Fgfr1tm1Jpa/Fgfr1tm1Jpa, Fgfr2tm1Dor/Fgfr2tm1Dor (more )
Structure Level Pattern Image Note
TS21: lens anterior epithelium Strong 4B High levels of expression in anterior epithelium and equatorial lens fiber cells.
TS21: posterior lens fiber Strong 4B High levels of expression in anterior epithelium and equatorial lens fiber cells.
Specimen 4C: embryonic day 16.5; Fgfr1tm1Jpa/Fgfr1tm1Jpa, Fgfr2tm1Dor/Fgfr2tm1Dor, Fgfr3tm1Dor/Fgfr3tm1Dor, Tg(Cryaa-cre)10Mlr/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: lens Present Uniform 4C Expression unformly distributed.
Specimen 4D: embryonic day 16.5; Fgfr1tm1Jpa/Fgfr1tm1Jpa, Fgfr2tm1Dor/Fgfr2tm1Dor (more )
Structure Level Pattern Image Note
TS24: lens anterior epithelium Strong 4D High levels of expression in anterior epithelium and equatorial lens fiber cells.
TS24: posterior lens fiber Strong 4D High levels of expression in anterior epithelium and equatorial lens fiber cells.
TS24: anterior lens fiber Weak 4D Reduced levels of expression in more mature lens fiber cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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