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Gene Expression Data
Assay Details
Assay
Reference: J:186496 Oommen S, et al., Distinct roles of MicroRNAs in epithelium and mesenchyme during tooth development. Dev Dyn. 2012 Sep;241(9):1465-72
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6381656
Gene symbol: Smad9
Gene name: SMAD family member 9
Antibody: Anti-Phospho-Smad1/5/8
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Assay notes: The antibody used recognizes the phosphorylated form of the protein. Antibody recognizes multiple gene products; Smad1 (assay MGI:6381654) and Smad5 (assay MGI:6381655) have also been annotated. The Tyramide signal amplification system was used.
Results
Specimen 3C: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: upper jaw incisor Present 3C
Specimen 3D: embryonic day 17.5; Dicer1tm1Bdh/Dicer1tm1Bdh, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS25: upper jaw incisor Present 3D Expression in the upper maxillary incisor was not significantly changed in the mutant tooth germ.
Specimen 3E: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: lower jaw incisor Present 3E
Specimen 3F: embryonic day 17.5; Dicer1tm1Bdh/Dicer1tm1Bdh, H2az2Tg(Wnt1-cre)11Rth/H2az2+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS25: lower jaw incisor Absent 3F
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory