About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:279375 Fritz KR, et al., Cdc42 activation by endothelin regulates neural crest cell migration in the cardiac outflow tract. Dev Dyn. 2019 Sep;248(9):795-812
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6379665
Gene symbol: Cdc42
Gene name: cell division cycle 42
Antibody: anti-Cdc42
Detection system: Alexa Fluor
Results
Specimen 11 Cdc42 WT: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: cardiac neural crest Present Regionally restricted 11_Cdc42 WT Expression localized mainly at anterior migratory front of cardiac neural crest cells (CNCC). Expression accumulates at edge of cells in stream of CNCC migrating along outflow tract, but not in CNCC within pharyngeal arches.
Specimen 11 Cdc42 Ednra-/-: embryonic day 9.5; Ednratm1Ywa/Ednratm1Ywa (more )
Structure Level Pattern Image Note
TS15: cardiac neural crest Present Regionally restricted 11_Cdc42 Ednra-/- Expression fails to localize at leading edges of migrating cardiac neural crest cells (CNCC).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory